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过敏性疾病与肠道菌群失调的相关性及对过敏体质研究的启示

杨菲 王济 王琦

北京中医药大学学报Issue(8):509-514,6.
北京中医药大学学报Issue(8):509-514,6.DOI:10.3969/j.issn.1006-2157.2015.08.001

过敏性疾病与肠道菌群失调的相关性及对过敏体质研究的启示

Allergic diseases and intestinal flora imbalance for allergic constitution research

杨菲 1王济 1王琦1

作者信息

  • 1. 北京中医药大学基础医学院中医体质与生殖医学研究中心 北京 100029
  • 折叠

摘要

Abstract

Studies have shown that intestinal flora imbalance is closely related with allergic diseases,yet its specific mechanism remains unclear.Modern medicine considers that it may be associated with in-creased intestinal permeability and intestinal barrier disruption caused by dendritic cells and other im-mune cells.Traditional Chinese Medicine identifies three possible approaches,which are “Lungs invaded by evil passing to the large intestine”,“Spleen invaded by evil leading to restricted nutrition and dis-turbed microenvironment”and “Liver invaded by evil leading to stirred-up wind and disturbed microenvi-ronment”.The root cause is that “Pathogenic factor invades when Zheng Qi is deficient”.This paper ex-plores what intestinal flora research can bring to the allergic constitution study by combining the four fun-damental theories “Life course theory”,“Composition of form and spirit”,“Environmental constraint theory”,and “Theory of innate endowment”.

关键词

过敏性疾病/食物过敏/肠道菌群/过敏体质/启示

Key words

allergic diseases/food allergies/intestinal flora/allergic constitution/implications

分类

医药卫生

引用本文复制引用

杨菲,王济,王琦..过敏性疾病与肠道菌群失调的相关性及对过敏体质研究的启示[J].北京中医药大学学报,2015,(8):509-514,6.

基金项目

国家自然科学基金面上项目 ()

北京中医药大学学报

OA北大核心CSCDCSTPCD

1006-2157

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