摘要
Abstract
Objective To analyze the epidemiological characteristics of helicobacter pylori (Hp) infection in children in Yulin and to provide guidance for the prevention and treatment of Hp infection and related diseases.Methods Between January 1, 2012 and December 31, 2014 totally 9 733 healthy children and infected cases visited Yulin Children' s Hospital, and Hp infection was detected by 13C-ura breath test (13C-UBT) and was analyzed combining clinical data.Results The overall infection rate of Hp was 45.67%in Yulin, and that of healthy children was 21.41%.The positive rate of Hp was 46.32%, 44.18%and 45.79%, respectively in 2012, 2013 and 2014.Hp infection was different among all age groups, and that was 38.33%and 49.47%in preschool period and school-age period.The positive rate of Hp was 45.55%for boys and 46.09%for girls.In urban area the positive rate was 40.15%, and it was 48.37% in rural area. The infection rate of digestive system was as high as 67.77%, and that of hematological system, respiratory system, cardiovascular system, immune system, urinary system and neurological system was 35.39%, 30.86%, 26.78%, 26.95%, 23.54% and 25.32%, respectively.The difference in Hp infection in digestive system, hematological system, respiratory system and immune system was significant between infected children and controls (χ2 value was 1 177.863, 58.679, 26.810 and 7.067, respectively, all P<0.01). Conclusion The infection rate of Hp in Yulin is lower than the national average natural infection rate.Hp infection rate of preschoolers is significantly lower than school-age children, and there is an increasing trend with age.It is not related with gender.Hp infection rate in urban is lower than in rural area.Hp infection rate is different among different system diseases, and the highest prevalence is found in digestive diseases.Therefore, attention should be paid to the prevention and treatment of the bacteria during the diagnosis and treatment of related diseases.关键词
儿童/幽门螺杆菌/感染率/流行病学Key words
children/helicobacter pylori ( Hp)/infection rate/epidemiology分类
医药卫生