摘要
Abstract
Objective To compare the clinical characteristics of respiratory distress syndrome ( RDS ) between gestational age <35w premature neonates and term and late-preterm neonates and the differences among them.Methods Eighty-nine cases of RDS admitted in People's Hospital of Lanxi City during the period of December 2011 to December 2013 were divided into two groups:term and late-preterm neonate group (gestational age≥35w, n=32) and gestational age<35w premature neonate group (gestational age<35w, n=57).The risk factors, onset time, treatment and complications of them were analyzed.Results Premature was the main etiology of RDS in gestational age<35w premature neonates, while cesarean section was the major high risk factor in term and late-preterm neonates (59.4%), followed by asphyxia, meconium aspiration and gestational diabetes mellitus (χ2 value was 6.52, 6.47, 9.24 and 4.15, respectively, all P<0.05).The occurrence of RDS was later (t=3.92,P<0.01) and the start time to use CPAP or ventilator was also later (t=4.20, P<0.01) in term and late-preterm neonate group than in gestational age<35w premature neonate group.But the continuous application of ventilator was longer (t=2.27,P<0.05) in term and late-preterm neonates, and they were more likely to suffer pneumothorax (χ2 =5.82,P<0.05) and persistent pulmonary hypertension (PPHN) (χ2 =9.49,P <0.01).Conclusion Cesarean section, meconium aspiration, asphyxia and gestational diabetes mellitus are the risk factors of term and late-preterm neonates with RDS.The onset time for RDS is late and mechanical ventilation is long in term and late-preterm neonates, who are likely to suffer pneumothorax and PPHN. Therefore, active preventing neonates asphyxia and meconium aspiration, and reducing cesarean section rate can significantly reduce the occurrence of RDS among term and late-preterm neonates.Meanwhile, it is important to improve clinician' s awareness on RDS to achieve early diagnosis and early treatment as well as better prognosis.关键词
晚期早产儿/足月儿/胎龄<35周早产儿/呼吸窘迫综合征/临床分析Key words
late-preterm neonates/gestational age<35w premature neonates/respiratory distress syndrome (RDS)/clinical analysis分类
医药卫生
