Abstract
Objective To explore the influence of hysterectomy and bilateral salpingectomy on ovarian function.Methods During January 2011 to June 2012 262 patients needing hysterectomy because of uterine benign disease in Shaanxi Province Maternity and Child Care Hospital and First Hospital of Hanbin District in Ankang City were selected in the study, including 138 cases who underwent hysterectomy and bilateral salpingectomy in study group and 124 cases who underwent hysterectomy alone in control group.Their operation time, intraoperative hemorrhage, postoperative exhaust time and postoperation hospitalization duration were recorded.All patients were followed up after 1, 3, 6 and 12 months, and they were asked whether they had perimenopausal syndrome.Meanwhile their serum sex hormone levels were tested including FSH, LH and E2 .Results There were no statistical differences between two groups in operation time, intraoperative hemorrhage, postoperative exhaust time and postoperation hospitalization duration (t value was -0.460, 0.316, 0.389 and 0.167, respectively, all P>0.05).Preoperative FSH, LH and E2 levels of two groups showed no significant differences(t value was-0.575, -0.539 and -1.967, respectively, all P>0.05).Both FSH and LH levels of the study group rose after 1, 3, 6 and 12 months(t value was -3.679, -7.374, 18.181, 25.133, -5.688, -13.182, -16.181 and -40.089, respectively, all P<0.05), and those of the control group rose too(t value was -4.479, -12.833, -13.202, -22.363,-5.600, -9.972, -17.369 and-34.448, respectively, all P<0.05).But E2 levels of two groups decreased (t value was 2.243, 3.087, 3.679, 5.068, 1.999, 5.169, 9.634 and 11.183, respectively, all P<0.05).There were no statistical significances between two groups in FSH, LH and E2 levels 1, 3, 6 and 12 months after operation ( t value was -1.627, -3.945, 2.114, 3.458, -1.750, 0.207, 0.528, 0.62, -2.911, 0.356, 3.567, 4.913.all P >0.05).Both groups had incidence of perimenopausal symptoms during follow -up periods, but the difference was not significant (χ2 value was 17.411, 163.622, 89.321 and 42.110, respectively, all P >0.05 ) .Conclusion Hysterectomy has influence on ovarian function, but resection of bilateral oviducts at the same time will not aggravate the effect.As a result, hysterectomy plus resection of the oviducts which are normal in appearance can prevent the happening of carcinoma of the fallopian tubes and ovarian tumors.Conventional resection is recommended especially for the patients who have risk factors or family history of ovarian tumors.关键词
子宫切除术/输卵管/围绝经期/卵巢功能Key words
hysterectomy/fallopian tubes/perimenopausal period/ovarian function分类
医药卫生
