中国妇幼健康研究2015，Vol.26Issue(4)：893-895,3.DOI:10.3969/j.issn.1673-5293.2015.04.086
促红细胞生成素与早产儿脑白质损伤的关系研究
Relationship between erythropoietin and white matter damage of premature infants
摘要
Abstract
White matter damage ( WMD) of premature infants is one of the significant causes leading to neurological disabilities, and imaging is the way to identify the disease.Up to now, researches have found that erythropoietin ( EPO) could not only improve brain development, but have protective effect on preterm neonatal brain injury.The fundamental mechanism of EPO is its ability of inhibiting apoptosis, anti-oxidation, anti-inflammatory, anti-epilepsy, and angiogenesis.Meanwhile, there are gene polymorphisms in EPO gene, which maybe relate with the individual susceptibility difference in WMD of premature infants.关键词
早产儿/脑白质损伤/促红细胞生成素/基因多态性Key words
premature infants/white matter damage ( WMD)/erythropoietin ( EPO)/gene polymorphisms分类
医药卫生引用本文复制引用
任青,卢宪梅..促红细胞生成素与早产儿脑白质损伤的关系研究[J].中国妇幼健康研究,2015,26(4):893-895,3.基金项目
国家自然科学基金资助项目(11471152) （11471152）
