激光生物学报Issue(3)：207-219,13.DOI:10.3969/j.issn.1007-7146.2015.03.001
几种先进的光学纳米探针在光学生物诊疗中的应用
Using Some Nanoparticles as Optical Probes for Optical Bioimaging
摘要
Abstract
The employment of nanometric optical probes is powerful for bioimaging, disease diagnosis and therapy, es-pecially for the deep understanding of some dynamic biological processes at the molecular level. Optical probes such as gold nanorods (GNRs), upconversion nanoparticles (UCNPs) and graphene oxide (GO) can overcome many draw-backs of conventional optical agents. These nanoparticles possess high imaging contrast, stability and biocompatibility. Furthermor, they provide optical approaches for deep-tissue imaging and real-time dynamic imaging. In this review pa-per, the optical properties and advantages of these nanoparticles are briefly introduced, and some of their applications in optical bioimaging, diagnosis and therapy are summarized based on some of the research progress made by the authors and others. The prospects of their application are also discussed.关键词
光学探针/纳米颗粒/生物光学成像Key words
optical probes/nanoparticles/bioimaging分类
生物科学引用本文复制引用
詹求强,张欣,李心,何赛灵..几种先进的光学纳米探针在光学生物诊疗中的应用[J].激光生物学报,2015,(3):207-219,13.基金项目
国家自然科学基金(61405062) （61405062）
广东省自然科学基金(S2013040014211,2014A030313445) （S2013040014211,2014A030313445）
中国博士后科学基金(2013M530368,2014T70818) （2013M530368,2014T70818）
广东高校学科建设专项基金科研项目(2013LYM 0017) （2013LYM 0017）
华南师范大学青年教师培育基金(2012KJ017) （2012KJ017）
共青团华南师范大学2013-2014年度学生课外科研重点课题科研项目(13GDKC02) （13GDKC02）
