激光生物学报Issue(4)：335-340,381,7.DOI:10.3969/j.issn.1007-7146.2015.04.006
免散瞳眼底图像在糖尿病视网膜病变自动筛查中的应用∗
Research of Non-dilated Fundus Images for Automated Diabetic Retinopathy Screening
摘要
Abstract
In order to realize automatic screening for diabetic retinopathy ( DR ) , an automated diabetic retinopathy screening system based on non-dilated fundus images is proposed and studied. Firstly, the composition and key technol-ogy of the system including locating and extracting optic disc and automated detection of hard exudates, cotton wool spots, hemorrhages as well as microaneurysms were analyzed and reviewed. Then the system based on non-dilated fun-dus images was developed and tested on an image dataset collected in clinic which include 7 687 samples in total of 15 374 fundus images. With an exam-based criterion, sensitivity of 96. 46%, specificity of 96. 07% are achieved. Fur-thermore, the average time cost in processing a sample is 57. 87 seconds. Results suggest that the performance of DR screening system meet the minimum standard of 80% sensitivity and 95% specificity for the detection of sight-threaten-ing DR which was recommended by British Diabetic Association guidelines.关键词
免散瞳眼底图像/糖尿病视网膜病变/自动检测/自动筛查/图像分割Key words
non-dilated fundus images/diabetic retinopathy/automated detection/automated screening/image seg-mentation分类
医药卫生引用本文复制引用
高玮玮,程武山,沈建新,左晶,张爱华..免散瞳眼底图像在糖尿病视网膜病变自动筛查中的应用∗[J].激光生物学报,2015,(4):335-340,381,7.基金项目
中央高校基本科研业务费专项(NJ20120007) （NJ20120007）
江苏省普通高校研究生科研创新计划项目(CXLX11_0218)资助 （CXLX11_0218）
