吉林中医药Issue(9)：893-896,4.DOI:10.13463/j.cnki.jlzyy.2015.09.009
蜂胶总黄酮滴丸治疗慢性稳定性心绞痛气虚血瘀证疗效及安全性研究
Total flavonoids of propolis (TFP) pills in treating chronic stable angina with syndrome of qi deficiency and blood stasis
摘要
Abstract
Objective To study the clinical efficiency and evaluate the security of Total flavonoids of propolis(TFP) pills for the treatment of chronic stable angina (syndrome of qi deficiency and blood stasis ) by motion tablets .Methods Sixty four patients with stable angina pectoris type in CHD with the syndrome of qi deficiency and blood stasis were selected and divid-ed randomly into two groups:Treatment group ( n=48 ) treated with TFP pills;Control group ( n=16 ) treated with TFP analog agent .The trival lasted three months .Observing and comparing clinical symptoms effect changes between two groups and evaluate their security .Results Treadmill test:after treating ,total time of exercise ,the maximum HR during exercise test ,metabolic equivalent of treatment group were improved significantly than before ,with statistical difference ( P<0 .05 ) . The total time of exercise in treatment group was significantly longer than that in control group ,with statistical difference ( P<0 .05 ) .Alleviating angina pectoris:after treatments ,treatment group achieved 16 .67% obvious curative rate respec-tively ,and results effective rate of this group was 45 .83% .TCM symptoms curative effect ,symptom curative effect of TCM treatment group patients total effective rate was 75 .00% ;The control group total effective rate 25 .00% .After studying , anginal stability ,satisfaction on treatment ,and cognitive level on disease were higher than pre-treatment ,with statistical dif-ference ( P<0 .05 ,P<0 .01 );satisfaction on treatment in treatment group was higher than control group ,with statistical difference ( P<0 .05) .Conclusion Total flavonoids of propolis (TFP) pills have favorable clinical curative effect on angi-na pectoris of coronary heart disease .TFP can improve blood supply of cardiac muscle ,is effective in alleviating angina pec-toris and improving clinical symptoms ,and can enhance heart reserve ability ,raise the quality of life .关键词
慢性稳定性心绞痛/蜂胶总黄酮滴丸/运动平板/西雅图量表Key words
chronic stable angina/total flavonoids of propolis pills/motion tablet/Seattle Angina Questionnaire分类
医药卫生引用本文复制引用
郭金昊,杨传华,王静,季倩倩..蜂胶总黄酮滴丸治疗慢性稳定性心绞痛气虚血瘀证疗效及安全性研究[J].吉林中医药,2015,(9):893-896,4.基金项目
泰山学者岗位建设资金资助项目（2012－55）；山东省科技发展计划项目（2014GSF119011）。 （）
