检验医学与临床Issue(17)：2543-2544,2547,3.DOI:10.3969/j.issn.1672-9455.2015.17.024
利伐沙班对老年下肢骨折患者术后深静脉血栓形成发生率的影响
Influence of rivaroxaban on occurrence rate of postoperative DVT in elderly patients with lower limb fracture
周煜虎 1冯阳阳 1宋建华 1刘向栋1
作者信息
- 1. 延安大学附属医院骨科，陕西延安 716000
- 折叠
摘要
Abstract
Objective To explore the influence of rivaroxaban on deep vein thrombosis(DVT) occurrence rate in elderly patients with lower limb fracture .Methods A retrospective analysis was performed on the clinical data of 135 cases of elderly lower limb fracture treated by operation in our hospital from September 2013 to September 2014 . The patients were divided into control group(67 cases) and observation group(68 cases) according to the treatment schemes .The two groups were given the routine low molecular heparin sodium therapy and the rivaroxaban therapy respectively .The occurrence rate of DVT ,intraoperative bleeding volume and occurrence rate of adverse reactions were observed and compared between the two groups .Results The occurrence rates of DVT in the observation group and the control group were 2 .9% and 14 .9% respectively ,the observation group was significantly lower than the control group with statistical difference(P<0 .05);the drainage volumes on postoperative 1 ,2 d in the observation group were (210 .3 ± 42 .5)mL and (130 .2 ± 30 .1)mL respectively ,which were significantly less than (245 .8 ± 45 .6) ,(115 .6 ± 32 .8)mL in the control group ,the differences were statistically significant(P<0 .05) .No statistical‐ly significant difference between the two groups was found in the occurrence rate of adverse reactions (P> 0 .05) . Conclusion For elderly patients with lower limb fracture ,giving rivaroxaban can better reduce the occurrence rate of DV T .关键词
利伐沙班/老年患者/下肢骨折/深静脉血栓形成Key words
rivaroxaban/elderly patients/lower limb fracture/deep venous thrombosis引用本文复制引用
周煜虎,冯阳阳,宋建华,刘向栋..利伐沙班对老年下肢骨折患者术后深静脉血栓形成发生率的影响[J].检验医学与临床,2015,(17):2543-2544,2547,3.
