检验医学与临床Issue(18)：2684-2687,4.DOI:10.3969/j.issn.1672-9455.2015.18.015
老年胃癌患者胃切除术后并发症相关发病因素分析
Analysis of complications related pathogenic factors in elderly patients after gastrectomy with gastric cancer
摘要
Abstract
Objective To explore the complications related pathogenic factors after gastrectomy in the elderly patients with gastric cancer to provide references for the clinical diagnosis and treatment .Methods 318 patients un‐dergone gastric cancer resection in our hospital from January 2010 to January 2015 were selected as the research sub‐jects ,the patients aged over 65 year old were grouped as the aged group(112 cases) and the patients aged < 65 years old were classified as the control group(206 cases) .The clinicopathological indexes and perioperative period factors including operation time ,exhaust time ,lymph node metastasis ,postoperative hospitalization time ,etc .were evaluated . The comparison between groups adopted t test ,χ2 test or Fisher exact probability method .The influencing factors of postoperative complications occurrence rate were evaluated by using the Logistic regression analysis .Results The in‐cidence rate of postoperative complications in all enrolled patients was 14 .78% (47/318) ,which in the patients aged< 65 years old was 9 .22% (19/206) and which in the patients aged ≥ 65 years was 25 .00% (28/112) .The compari‐son results of clinical characteristics between the aged group and the control group showed that the comorbidities , tumor location ,Lauren type ,intraoperative blood transfusion and postoperative blood transfusion had the statistically significant differences between the two groups (P< 0 .05) .The operation time ,first exhaust time ,soft diet starting time and postoperative hospitalization time were the important factors affecting the gastrectomy results ,which had statistically significant differences between the two groups(P < 0 .05) .And lymph node metastasis number was not the main factor affecting gastrectomy results in elderly patients ,the difference between the two groups had no statis‐tical significance(P > 0 .05) .The postoperative complications ,hospitalization death rate and operative complications had statistically significant differences between the two groups(P< 0 .05) ,while the non‐operation complications had no statistical differences between the two groups (P> 0 .05) .According to the results of multiple Logistic regression analysis ,age(OR = 3 .57 ,95% CI :1 .15 - 16 .01 ,P= 0 .021) ,BMI (OR = 6 .62 ,95% CI :2 .76 - 21 .12 ,P= 0 .006) ,op‐eration time(OR = 0 .85 ,95% CI :0 .07 - 0 .97 ,P = 0 .042) ,postoperative blood transfusion (OR = 9 .73 ,95% CI :2 .17 - 18 .31 ,P= 0 .038) and invasion depth(OR = 7 .58 ,95% CI :2 .21 - 22 .16 ,P= 0 .029) the independent risk fac‐tors affecting the complications after gastrectomy in the elderly patients with gastric cancer .Conclusion Age ,BMI , operation time ,postoperative blood transfusion and invasion depth are the independent risk factors affecting the com‐plications after gastrectomy in the elderly patients with gastric cancer .关键词
胃癌/老年人/胃切除术/术后并发症/危险因素Key words
gastric cancer/the elderly/gastrectomy/postoperative complications/risk factors引用本文复制引用
叶景旺,付涛,王祥峰,童卫东..老年胃癌患者胃切除术后并发症相关发病因素分析[J].检验医学与临床,2015,(18):2684-2687,4.基金项目
重庆市自然科学基金资助项目（2008BB5101）。 （）
