检验医学与临床Issue(18)：2731-2733,3.DOI:10.3969/j.issn.1672-9455.2015.18.033
影像学诊断在类风湿关节炎患者中的应用研究
Research on application of imaging diagnosis in rheumatoid arthritis
刘卫宾 1刘海平1
作者信息
- 1. 河北省保定市第二中心医院放射科 072750
- 折叠
摘要
Abstract
Objective To investigate the application situation of imaging diagnosis of MRI ,CT ,etc .in rheuma‐toid arthritis(RA) .Methods 70 patients with RA in our hospital were selected and their clinical data were collected . The related antibodies and inflammatory reaction indicators were detected .The disease activity situation was as‐sessed .At the same time the imaging examinations such as MRI and SPECT /CT were performed .The MRI images were scored according to the RAMRIS system .The bone metabolism increasing area was performed the region of in‐terest (ROI) analysis for calculating the uptake ratio of ROI .Results The Spearman correlation of SDAI and RAM‐RIS :synovitis (ρ = 0 .391 ,P< 0 .05) ,bone marrow edema(BME) (ρ = 0 .402 ,P< 0 .05) and erosion(ρ = 0 .329 ,P=0 .006) .The RAMRIS score had statistical difference between SDAI < 11 (low disease activity and remission) and SDAI ≥ 11 group(moderate and severe disease activity) (P= 0 .002) .The SPECT /CT in vivo uptake had the correla‐tion with the body inflammatory factors of ESR and CRP (ρ = 0 .343 ,P< 0 .05 ,ρ = 0 .431 ,P< 0 .05) ;and the uptake was also significantly correlated with the anti‐inflammatory cytokine AKA (ρ = 0 .263 ,P< 0 .05) .In addition ,the up‐take rate was also significantly correlated with the disease activity SDAI(ρ = 0 .355 ,P< 0 .05) .Conclusion The ima‐ging methods of MRI and CT conduce to early diagnosis of RA and the uptake rate of MRI and SPECT /CT has posi‐tive significance to evaluate the progression and prognosis of RA .关键词
类风湿关节炎/诊断/治疗/影像学方法Key words
rheumatoid arthritis/diagnosis/treatment/imaging methods引用本文复制引用
刘卫宾,刘海平..影像学诊断在类风湿关节炎患者中的应用研究[J].检验医学与临床,2015,(18):2731-2733,3.
