临床神经病学杂志Issue(4)：251-254,4.
负性情绪刺激对发作间期偏头痛患者Gamma 振荡的脑磁图研究
Magnetoencephalography study of Gamma-oscillation to negative emotional stimuli in patients with interictal migraine
范捷 1祝东林 1杨露 2吴婷 3石静萍1
作者信息
- 1. 210029南京医科大学附属脑科医院神经内科
- 2. 210029南京医科大学附属脑科医院脑磁图中心
- 折叠
摘要
Abstract
Objective To investigate the influence of Gamma-oscillation to negative emotional stimuli in patients with interictal migraine.Methods The Gamma-band oscillatory signatures of neuromagnetic activity of magnetoencephalography were recorded that evoked by positive, neuter and negative facial expressions pictures in 30 patients in interictal migraine and 30 age and gender matched controls.Migraine patients were assessed by Hamilton anxiety scale ( HAMA) and Hamilton depression scale ( HAMD) .Results Compared with normal control group, the averaged spectral power in both low and high Gamma oscillatory responses to negative emotional stimuli in M100 time window of migraine group were significantly decreased (t=-2.319,P=0.024;t=-2.610,P=0.012), and the averaged spectral power in both low and high Gamma oscillatory responses to negative emotional stimuli in M170 time window of migraine group were also significantly decreased (t=-2.233,P=0.029;t=-2.299,P=0.025). The averaged spectral power in both low and high Gamma oscillatory responses to negative emotional stimuli in M100 time window had negative correlation with HAMD score (r=-0.480,P=0.007;r=-0.407,P=0.025), and the averaged spectral power in both low and high Gamma oscillatory responses to negative emotional stimuli in M100 time window had negative correlation with HAMD score (r=-0.593,P=0.001;r=-0.398,P=0.029).Conclusion The patients with interictal migraine have brain dysfunction in the processing of negative emotional stimuli, and this brain dysfunction is resulted from both migraine and emotional factors.关键词
偏头痛/脑磁图/情绪图片/Gamma振荡Key words
migraine/magnetoencephalography/affective pictures/Gamma oscillation分类
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范捷,祝东林,杨露,吴婷,石静萍..负性情绪刺激对发作间期偏头痛患者Gamma 振荡的脑磁图研究[J].临床神经病学杂志,2015,(4):251-254,4.
