临床神经病学杂志Issue(4):299-301,3.
早期强化降压治疗与高血压脑出血血肿、血肿周围水肿的关系
Relationship between early intensively antihypertensive therapy and hematoma, perihermatomal brain edema of hypertensive intracerebral hemorrhage
摘要
Abstract
Objective To explore the relationship between early intensively antihypertensive therapy and hematoma, perihermatomal brain edema of hypertensive intracerebral hemorrhage (HICH).Methods Fifty HICH patients were randomly divided into intensively antihypertensive therapy group ( 23 cases ) and control group ( 27 cases). All patients were given conventional treatment, and intensively antihypertensive therapy group was administrated with 10 mg amlodipine orally per day additonally.Brain CT was performed at admission and 24 h later. Volume of hematoma and perihermatomal brain edema were compared between the two groups.Results The systolic pressure, volume of hematoma and perihermatomal brain edema of intensively antihypertensive therapy group had no significant differences compared with the control group at admission (all P>0.05).Compared with control group, systolic pressure, volume of hematoma andperihermatomal brain edema of intensively antihypertensive therapy group were significantly lower at 24 h after admission ( all P<0.05 ) .Pearson correlation analysis showed a positive correlation between SBP and volume of hematoma, perihermatomal brain edema( r=0.291, P=0.040; r=0.312, P=0.027 ) .Conclusion Early intensively antihypertensive therapy can reduce the volume of hematoma and perihermatomal brain edema of HICH.关键词
早期强化降压/高血压脑出血/关系Key words
early intensively antihypertensive therapy/hypertensive intracerebral hemorrhage/relationship分类
医药卫生引用本文复制引用
刘佳佳,黎宏斐,沈福玉,黄伟,吴丽玲,王圣岳..早期强化降压治疗与高血压脑出血血肿、血肿周围水肿的关系[J].临床神经病学杂志,2015,(4):299-301,3.基金项目
南京浦口区科技发展计划基金项目 ()