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早期强化降压治疗与高血压脑出血血肿、血肿周围水肿的关系

刘佳佳 黎宏斐 沈福玉 黄伟 吴丽玲 王圣岳

临床神经病学杂志Issue(4):299-301,3.
临床神经病学杂志Issue(4):299-301,3.

早期强化降压治疗与高血压脑出血血肿、血肿周围水肿的关系

Relationship between early intensively antihypertensive therapy and hematoma, perihermatomal brain edema of hypertensive intracerebral hemorrhage

刘佳佳 1黎宏斐 1沈福玉 1黄伟 1吴丽玲 1王圣岳1

作者信息

  • 1. 210031南京浦口医院神经内科
  • 折叠

摘要

Abstract

Objective To explore the relationship between early intensively antihypertensive therapy and hematoma, perihermatomal brain edema of hypertensive intracerebral hemorrhage (HICH).Methods Fifty HICH patients were randomly divided into intensively antihypertensive therapy group ( 23 cases ) and control group ( 27 cases). All patients were given conventional treatment, and intensively antihypertensive therapy group was administrated with 10 mg amlodipine orally per day additonally.Brain CT was performed at admission and 24 h later. Volume of hematoma and perihermatomal brain edema were compared between the two groups.Results The systolic pressure, volume of hematoma and perihermatomal brain edema of intensively antihypertensive therapy group had no significant differences compared with the control group at admission (all P>0.05).Compared with control group, systolic pressure, volume of hematoma andperihermatomal brain edema of intensively antihypertensive therapy group were significantly lower at 24 h after admission ( all P<0.05 ) .Pearson correlation analysis showed a positive correlation between SBP and volume of hematoma, perihermatomal brain edema( r=0.291, P=0.040; r=0.312, P=0.027 ) .Conclusion Early intensively antihypertensive therapy can reduce the volume of hematoma and perihermatomal brain edema of HICH.

关键词

早期强化降压/高血压脑出血/关系

Key words

early intensively antihypertensive therapy/hypertensive intracerebral hemorrhage/relationship

分类

医药卫生

引用本文复制引用

刘佳佳,黎宏斐,沈福玉,黄伟,吴丽玲,王圣岳..早期强化降压治疗与高血压脑出血血肿、血肿周围水肿的关系[J].临床神经病学杂志,2015,(4):299-301,3.

基金项目

南京浦口区科技发展计划基金项目 ()

临床神经病学杂志

OA北大核心CSTPCD

1004-1648

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