临床神经病学杂志Issue(4)：302-304,3.
老年起病橄榄体脑桥小脑萎缩的临床特点（附1例报告）
Clinical features of elderly onset olivopontocerebellar atrophy (report of 1 case)
彭巧玲 1段立晖 1何月 1孙芳 1严斌 1周国庆1
作者信息
- 1. 210002南京军区南京总医院神经内科干部病区
- 折叠
摘要
Abstract
Objective To explore the clinical features of elderly onset olivopontocerebellar atrophy (OPCA). Methods The clinical data of 1 OPCA patient with elderly onset was analyzed retrospectively.Results This patient was female, 77 years old.The main clinical manifestations were frequent urination, nocturia, frequent uroschesis, walking instability, gait ataxia, stiff limbs, and associated with verbal not fluency, spit the word unclear.EMG showed the amplitude of compound muscle action potential of peroneal nerve in both side were reduced, the motor nerve conduction velocity ( MCV) was normal.The MCV of tibial nerve, ulnar nerve, median nerve in both side were normal.The sensory nerve conduction velocity ( SCV) of ulnar nerve in both side, median nerve in left side were normal.Somatosensory evoked potentials ( SEP) showed the deep sensory pathway of left upper limb and left lower limb were normal.The deep sensory pathway in cortex of right upper limb was suffered damage, and the deep sensory pathway of right lower limb was suffered damage.Brain MRI showed the diameters lines of each direct cerebellum in T1 WI sagittal and coronal were shortened.The ratio of pons and medulla oblongata line was significantly decreased. The radial lines of brainstem were significantly smaller than the ratio of anteroposterior diameter of fourth ventricle.It can found“cross sign” in pons in T2 WI.Conclusions The symptoms of OPCA are not typical in early stage.The main clinical manifestations are weakness in both lower limb and progressive cerebellar ataxia, and associated with dysautonomia.The brain MRI feature is “cross sign”.关键词
橄榄体脑桥小脑萎缩/临床特点Key words
olivopontocerebellar atrophy/clinical feature分类
医药卫生引用本文复制引用
彭巧玲,段立晖,何月,孙芳,严斌,周国庆..老年起病橄榄体脑桥小脑萎缩的临床特点（附1例报告）[J].临床神经病学杂志,2015,(4):302-304,3.
