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首页|期刊导航|世界中医药|清脂颗粒干预酒精性脂肪肝形成的实验研究及对大鼠血清 TNF-α、Leptin 水平的影响

清脂颗粒干预酒精性脂肪肝形成的实验研究及对大鼠血清 TNF-α、Leptin 水平的影响

刘维明 刘相花 王玉娟 于丽丽 李秀丽 薛杰 侯殿俊

世界中医药Issue(8):1231-1234,4.
世界中医药Issue(8):1231-1234,4.DOI:10.3969/j.issn.1673-7202.2015.08.025

清脂颗粒干预酒精性脂肪肝形成的实验研究及对大鼠血清 TNF-α、Leptin 水平的影响

Experimental Study of Qingzhi Granule on the Formation of Alcoholic Fatty Liver and Its Effect on the Level of Rat Serum TNF-ɑand Leptin

刘维明 1刘相花 1王玉娟 1于丽丽 1李秀丽 1薛杰 2侯殿俊3

作者信息

  • 1. 山东中医药大学附属济南市中医医院消化科,济南,250012
  • 2. 山东中医药大学,济南,250014
  • 3. 山东省医学科学研究院,济南,250062
  • 折叠

摘要

Abstract

Objective:To investigate the effect and mechanism of traditional Chinese medicine Qingzhi granule on rats with alco-holic fatty liver.Methods:The composite molding method was used to induce alcoholic fatty liver rat model,and they were treated with traditional Chinese medicine Qingzhi granule intervention.The changes of liver histopathology and blood lipid,liver function, cytokine leptin Leptin and tumor necrosis factor alpha TNF-etc were observed.Conclusion:Traditional Chinese medicine Qingzhi granules can achieve the goal of the prevention and treatment of alcoholic fatty liver by improving blood lipid,liver function,and reducing serum TNF-α,Leptin level.

关键词

清脂颗粒/酒精性脂肪肝/实验研究

Key words

Qingzhi granule/Alcoholic fatty liver/Experimental study

分类

医药卫生

引用本文复制引用

刘维明,刘相花,王玉娟,于丽丽,李秀丽,薛杰,侯殿俊..清脂颗粒干预酒精性脂肪肝形成的实验研究及对大鼠血清 TNF-α、Leptin 水平的影响[J].世界中医药,2015,(8):1231-1234,4.

基金项目

山东省中医药管理局中医药发展计划项目 ()

世界中医药

OACHSSCDCSTPCD

1673-7202

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