世界中医药Issue(8)：1254-1256,1260,4.DOI:10.3969/j.issn.1673-7202.2015.08.031
中药治疗高尿酸血症随机对照试验的系统评价
Systematic Review of Randomized Controlled Trials of Chinese medicine in the Treatment of Hyperuricemia
霍晶晶 1王丽 1于世家1
作者信息
- 1. 辽宁中医药大学附属医院内分泌科，沈阳，110032
- 折叠
摘要
Abstract
Objective:Using evidence-based medicine system to make an impersonal evaluation on the validity of Chinese medi-cine in the treatment of hyperuricemia.Methods:Randomized controlled trials(RCT)on Chinese medicine’s efficacy on treating hyperruricemia were retrieved from domestic medicinal journals (1 980 -201 4)and then were evaluated through meta-analysis. Results:Ten studies involved 1 000 patients were identified.The results showed that there was significant difference between using Chinese medicine and routine chemical to treat hyperruricemia:(P =0.1 6,[OR =2.58,95%CI (1 .58,4.21 )]).The meta-a-nalysis result of reducing the level of blood uric acid was [SMD =SMD =-0.58,95%CI(-0.90,-0.26),Z =3.53,(P =0. 0004)].The differences between treatment group and control group were of statistical significance.Conclusion:In both the as-pects of total clinical efficacy and blood uric acid level reduction,the performance of treatment groups (using Chinese medicine) was better than the control groups (using chemical drugs).However,because some of the RCTs reviewed in this study did not ful-fill the strict requirement of evidence-based medicine,the results of this study can have deviation.Therefore,more qualified re-search with large sample were expected to evaluate these results.关键词
中医药/高尿酸血症/系统评价Key words
Chinese Medicine/Hyperuricemia/Systematic Review分类
医药卫生引用本文复制引用
霍晶晶,王丽,于世家..中药治疗高尿酸血症随机对照试验的系统评价[J].世界中医药,2015,(8):1254-1256,1260,4.
