实用医学杂志2015，Vol.31Issue(16)：2630-2633,4.DOI:10.3969/j.issn.1006-5725.2015.16.014
不同辅助生殖助孕技术的妊娠结局比较
Comparison of the safty of different assisted reproductive technologies
摘要
Abstract
Objective To compare the pregnancy outcomes of in vitro fertilization- embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI). Methods A retrospective analysis from January 2010 to January 2014 for 9 973 IVF-ET and 1 368 ICSI treatment cycles were collected. In the IVE and ICSI groups , we compared the implantation, clinical pregnancy, multiple pregnancy, ectopic pregnancy, abortion, premature birth, malformation rates, and sex ratio. Results The implantation rate (33.42%, 31.53%), clinical pregnancy rate (50.00%, 47.30%), abortion rate (13.93%, 11.50%), premature birth rate (25.04%, 23.26%), sex ratio (115:100, 103:100) and malformation rates (1.05%, 0.76%) were no statistically significant between the IVF-ET group and the ICSI group (P>0.05). The ectopic pregnancy rate (3.75%, 1.76%), multiple pregnancy rate (38.54%, 32.44%), low birth weight infants rate (32.07%, 26.86%) were increased significantly in the IVF group than the ICSI group (P<0.05 or P<0.01). Conclusions IVF and ICSI micromanipulation did not increase the risk of pregnancy. But the multiple pregnancy rate, ectopic pregnancy rate,low birth weight infants rate were increased significantly in the IVF group than the ICSI group.关键词
辅助生殖技术/体外受精-胚胎移植/卵母细胞浆内单精子注射/畸形/多胎妊娠Key words
Assisted reproductive technologies/In vitro fertilization-embryo transfer/Single sperm Injection in oocytes/Congenital malformations/Multiple pregnancies引用本文复制引用
康祥锦,丁悦,杨洁,刘寒艳,杜红姿,刘见桥,安庚..不同辅助生殖助孕技术的妊娠结局比较[J].实用医学杂志,2015,31(16):2630-2633,4.基金项目
国家自然科学基金资助项目(编号:81401254) （编号:81401254）
广州市教育局资助项目(编号:1201430205) （编号:1201430205）
广东省高等学校科技创新项目(编号:2012KJCX0087 ) （编号:2012KJCX0087 ）
