实用医学杂志2015,Vol.31Issue(16):2648-2650,3.DOI:10.3969/j.issn.1006-5725.2015.16.019
复合辅酶对2型心肾综合征患者心肾功能的影响
Effect of coenzyme complex on cardiac and renal functions of patients with type 2 cardiorenal syndrome
摘要
Abstract
Objective To investigate the effect of coenzyme complex on the cardiac and renal functions of patients with type 2 cardiorenal syndrome. Methods Sixty-two patients with type 2 cardiorenal syndrome were enrolled in from June 2013 to December 2014 in Zhujiang Hospital , Southern Medical University. These patients divided were into routine group (n = 31) and coenzyme complex (n = 31). The therapy scheme of coenzyme complex group was on the basis of routine group with coenzyme complex intravenous drip , 400 U/day for 2 weeks. The cardiac function was determined by New York Heart Function Assessment, and the cardiac ultrasound, the levels of BNP. The renal function was determined by serum creatinine and urine volume. Results Compared with routine group, the rates of NYHA Ⅲ and Ⅳ were reduced, the LVEF levels were increased and the levels of BNP were increased (P < 0.05). The serum creatinine was decreased and urine volume were increased in the coenzyme complex group (P<0.05). Conclusion Coenzyme complex could improve the cardiac and renal functions of the patients with type 2 cardiorenal syndrome.关键词
2型心肾综合征/复合辅酶/心功能/肾功能Key words
Type 2 cardiorenal syndrome/Coenzyme complex/Cardiac function/Renal function引用本文复制引用
王佳,陈若峰,郭建浩,周立尧,谭竹君,李志樑..复合辅酶对2型心肾综合征患者心肾功能的影响[J].实用医学杂志,2015,31(16):2648-2650,3.基金项目
广东省自然科学基金(编号:S2012010009326) (编号:S2012010009326)