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复合辅酶对2型心肾综合征患者心肾功能的影响

王佳 陈若峰 郭建浩 周立尧 谭竹君 李志樑

实用医学杂志2015,Vol.31Issue(16):2648-2650,3.
实用医学杂志2015,Vol.31Issue(16):2648-2650,3.DOI:10.3969/j.issn.1006-5725.2015.16.019

复合辅酶对2型心肾综合征患者心肾功能的影响

Effect of coenzyme complex on cardiac and renal functions of patients with type 2 cardiorenal syndrome

王佳 1陈若峰 1郭建浩 1周立尧 1谭竹君 1李志樑2

作者信息

  • 1. 528311 广东省佛山市顺德区北滘医院心血管内科
  • 2. 510282 广州市,南方医科大学珠江医院心血管内科
  • 折叠

摘要

Abstract

Objective To investigate the effect of coenzyme complex on the cardiac and renal functions of patients with type 2 cardiorenal syndrome. Methods Sixty-two patients with type 2 cardiorenal syndrome were enrolled in from June 2013 to December 2014 in Zhujiang Hospital , Southern Medical University. These patients divided were into routine group (n = 31) and coenzyme complex (n = 31). The therapy scheme of coenzyme complex group was on the basis of routine group with coenzyme complex intravenous drip , 400 U/day for 2 weeks. The cardiac function was determined by New York Heart Function Assessment, and the cardiac ultrasound, the levels of BNP. The renal function was determined by serum creatinine and urine volume. Results Compared with routine group, the rates of NYHA Ⅲ and Ⅳ were reduced, the LVEF levels were increased and the levels of BNP were increased (P < 0.05). The serum creatinine was decreased and urine volume were increased in the coenzyme complex group (P<0.05). Conclusion Coenzyme complex could improve the cardiac and renal functions of the patients with type 2 cardiorenal syndrome.

关键词

2型心肾综合征/复合辅酶/心功能/肾功能

Key words

Type 2 cardiorenal syndrome/Coenzyme complex/Cardiac function/Renal function

引用本文复制引用

王佳,陈若峰,郭建浩,周立尧,谭竹君,李志樑..复合辅酶对2型心肾综合征患者心肾功能的影响[J].实用医学杂志,2015,31(16):2648-2650,3.

基金项目

广东省自然科学基金(编号:S2012010009326) (编号:S2012010009326)

实用医学杂志

OA北大核心CSTPCD

1006-5725

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