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血清锌与儿童注意缺陷多动障碍关系的Meta分析

孙桂香 王炳花 张亚峰

中国当代儿科杂志Issue(9):980-983,4.
中国当代儿科杂志Issue(9):980-983,4.DOI:10.7499/j.issn.1008-8830.2015.09.019

血清锌与儿童注意缺陷多动障碍关系的Meta分析

Relationship between serum zinc levels and attention deifcit hyperactivity disorder in children

孙桂香 1王炳花 1张亚峰2

作者信息

  • 1. 徐州医学院公共卫生学院流行病学教研室,江苏徐州 221000
  • 2. 徐州医学院研究生学院,江苏徐州 221000
  • 折叠

摘要

Abstract

Objective To study the possible relationship between serum zinc levels and attention deficit hyperactivity disorder (ADHD) in Chinese children. Methods Following a systematic search for case-control studies on the serum zinc levels in Chinese children with ADHD published between 2000 and 2015, a Meta analysis was conducted using Stata 12.0 software. Results A total of 17 studies, including 2 177 children with ADHD and 2 900 normal children, were enrolled. The Meta analysis showed that serum zinc levels in children with ADHD were lower than normal children (SMD=-1.33;95%CI:-2.22,-0.44;P=0.003). The sensitivity analysis indicated that the results were reliable. Egger's test did not ifnd the existence of publication bias. Conclusions Serum zinc levels may be associated with susceptibility to ADHD in children.

关键词

注意缺陷多动障碍/血清锌/Meta分析/儿童

Key words

Attention deifcit hyperactivity disorder/Serum zinc/Meta analysis/Child

引用本文复制引用

孙桂香,王炳花,张亚峰..血清锌与儿童注意缺陷多动障碍关系的Meta分析[J].中国当代儿科杂志,2015,(9):980-983,4.

基金项目

江苏高校哲学社会科学研究基金项目(2012SJB190015)。 ()

中国当代儿科杂志

OA北大核心CSCDCSTPCDMEDLINE

1008-8830

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