肝动脉化疗栓塞术联合索拉菲尼治疗肝细胞肝癌的临床疗效与安全性评价OA北大核心CSCDCSTPCD
Efficacy and safety of transarterial chemoembolization combined with sorafenib in patients with hepatocellular carcinoma
目的:评价经导管肝动脉化疗栓塞术( TACE)联合索拉非尼治疗肝细胞肝癌的疗效和安全性。方法入选57例原发性肝细胞肝癌患者,其中23例行TACE联合索拉菲尼治疗(试验组),34例行单纯TACE治疗(对照组),对照组用阿霉素类药物20~40 mg化疗,超液化碘油剂量5~20 mL。如果患者需要进行多次TACE治疗,每次TACE治疗的时间间隔约为45 d。试验组在对照组基础上,第1次TACE治疗后72 h内口服索拉非尼400 mg,早、晚各服1次,连…查看全部>>
Objective To evaluate the efficacy and safety of transarterial chemoembolization ( TACE ) combined with sorafenib in patients with hepatocellular carcinoma.Methods A total of 57 patients with hepato-cellular carcinoma were divided into control group ( n =34 ) and treat-ment group ( n=23 ).Patients in the treatment group were treated with TACE ( doxorubicin 20-40 mg and lipiodol 5-20 mL) combined with oral sorafenib 400 mg within the 72 h after the first TACE…查看全部>>
马丽丽;韩忠诚;柳江
新疆维吾尔自治区人民医院 肿瘤科,乌鲁木齐830001新疆维吾尔自治区人民医院 肿瘤科,乌鲁木齐830001新疆维吾尔自治区人民医院 肿瘤科,乌鲁木齐830001
医药卫生
化学栓塞癌症肝细胞索拉非尼
chemoembolizationcarcinomahepatocellularsorafenib
《中国临床药理学杂志》 2015 (15)
1497-1499,3
新疆维吾尔自治区人民医院科研基金资助项目(20120122)
评论