中国全科医学Issue(26)：3192-3195,4.DOI:10.3969/j.issn.1007-9572.2015.26.017
高分级动脉瘤性蛛网膜下腔出血颅内夹闭术与介入治疗的近期预后对比研究
Prognosis of Patients With High-grade Aneurysmal Subarachnoid Hemorrhage Treated by Intracranial Surgery Using Clipping Method or Guglielmi Detachable Coils:A Comparative Study
摘要
Abstract
Objective To investigate the therapeutic effect of surgeries using clipping method and guglielmi detachable coils(GDC)on patients with high -grade aneurysmal subarachnoid hemorrhage(aSAH). Methods A total of 115 aSAH patients who received treatment in the Department of Neurosurgery,the Affiliated Hospital of Chengde medical University from January 2011 to October 2014 and who were of WFNS( World Federation of Neurosurgical Societies) gradeⅣ-Ⅴwere enrolled and divided into treatment group(n=60)and control group(n=55). The treatment group was given GDC,and the control group was administrated with clipping method. Embolism degree and complications were observed and recorded. Three -month follow-up was conducted to record Glasgow Outcome Scale ( GOS ) scores. Results The two groups were not significantly different in embolism degree(U=1. 55,P=0. 46). No death occurred in both groups during surgeries. The two groups were not significantly different(P>0. 05)in the deterioration of focal neural function,hydrocephalus and the incidence of rebleeding;the treatment group was lower(P<0. 05)than control group in the incidence of cerebral angiospasm. The treatment group was superior to the control 3 months after surgery(U =8. 19,P =0. 04). The treatment group was superior to the control in the grade-Ⅳ patients(U=12. 10,P=0. 01),and there was no significant difference between the two groups in the grade-Ⅴpatients(U=1. 06,P=0. 78). Conclusion The two surgical strategies on aSAH both have reliable curative effect and high safety,while high-grade aSAH patients who receive surgery using GDC has better quality of life in short-term outcomes.关键词
蛛网膜下腔出血/颅内动脉瘤/夹闭术/介入治疗Key words
Subarachnoid hemorrhage/Intracranial aneurysm/Clamp operation/Interventional therapy分类
医药卫生引用本文复制引用
呼铁民,于淼,张继伟,谢云鹏,马志君,胡军,季东鑫,王广..高分级动脉瘤性蛛网膜下腔出血颅内夹闭术与介入治疗的近期预后对比研究[J].中国全科医学,2015,(26):3192-3195,4.基金项目
承德市科学技术研究与发展计划（201422018）---不同手术方式对高危破裂颅内动脉瘤预后的影响 （）
