摘要
Abstract
Objective To investigate the value of multi -slice spiral CT( MSCT)coronary angiography with low iodine flow rate in plaque diagnosis. Methods Enrolled 30 patients with coronary heart diseases who undertook MSCT coronary angiography with low iodine flow rate in Shenzhen 4th People's Hospital from June 2013 to December 2014 and assigned them into low iodine flow group. Also enrolled another 30 patients with coronary heart diseases who undertook MSCT coronary angiography with normal iodine flow rate in the same period and assigned them into control group. With the same scanning condition and the same total amount of contrast medium,the two groups were examined with a iodine flow rate of 1 480 mgI/s and 1 850 mgI/s respectively(injection speeds were 4 ml/s and 5 ml/s). Workstation software was used to process images. The imaging quality, plaque indexes, contrast medium concentration and injection time were compared between the two groups. Results The two groups were not significantly different ( P >0. 05 ) in signal - to - noise ratio ( SNR ), carrier - to - noise ratio ( CNR ), imaging quality, imaging sharpness, plaque area ( PA ), plaque burden ( PB ), plaque eccentricity index and stenosis degree.Thetotalamountofcontrastmediumwas(68.5±4.9)mlforcontrolgroupand(56.8±6.3)mlforlowiodineflow group,with significant difference between the two groups(t=8. 067,P<0. 001). The injection time was(14. 4 ±1. 5)s for control group and(14.0 ± 0.9)s for low iodine flow group,with no significant difference between them(t =1.282,P=0. 205). Conclusion MSCT coronary angiography with low iodine flow rate could ensure the imaging quality required by diagnosis,reduce the usage of contrast medium,and reduce adverse reactions like contrast-induced nephropathy. It is valuable in clinical application.关键词
冠状血管造影术/多层螺旋CT/斑块,动脉粥样硬化/冠心病Key words
Coronary angiography/Multi slice spiral CT/Plaque,atherosclerotic/Coronary disease分类
医药卫生
