摘要
Abstract
OBJECTIVE:To establish early warning mechanisms of antibiotics drug resistance,and to provide reference for ra-tional drug use in the clinic. METHODS:The consumption amount of top 3 to 10 drugs in the list of consumption sum and amount in outpatient prescription and inpatient medical orders of our hospital during 2014 was analyzed statistically,including antibiotics, anti-tumor drugs,drugs for cardiovascular system,drugs for digestive system,biologicals. Top 5 Gram-positive bacterial and Gram-negative bacterial which induced infection in our hospital in Nov. 2014 was analyzed statistically in terms of resistant rate. RE-SULTS:Total consumption sum of drugs was 16 038.28 ten thousand yuan in our hospital in 2014,accounting for 27.95%;antibi-otics drugs accounted for 9.55%(1 531.44 ten thousand yuan) of total consumption sum,drugs for cardiovascular system 3.30%(529.60 ten thousand yuan),drugs for digestive system 8.32%(1 333.68 ten thousand yuan),anti-tumor drugs 2.93%(469.27 ten thousand yuan),and biologicals 3.50%(561.22 ten thousand yuan). 1 575 bacterial samples were detected in Nov. 2014,and bacte-rial were detected in 358 samples with positive rate of 22.73%. 136 Gram-positive bacterial were detected,and top 5 were Staphylo-coccus epidermidis, Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium and Streptococcus agalactiae. 222 Gram-negative bacterial were detected,and top 5 were Escherichia coli,Klebsiella pneumoniae,Acinetobacter baumannii,Hae-mophilus influenzae and Enterobacter cloacae. CONCLUSIONS:Five categories of drugs used in our hospital is rational compara-tively,and the proprotion of antibiotics in total consumption sum is much lower than other hospitals;control and standardization of antibiotics use has made some achievements.关键词
医院/治疗药物监测/抗菌药物/耐药性/合理用药Key words
Hospital/Therapeutic drug monitoring/Antibiotics/Drug resistance/Rational durg use分类
医药卫生
