中国药房Issue(26)：3655-3657,3.DOI:10.6039/j.issn.1001-0408.2015.26.16
HPLC法与微生物法测定人血浆中去甲万古霉素浓度的差异比较
Comparison of Plasma Concentration of Norvancomycin by HPLC and Microbiological Method
张开礼 1李成 1李玉珍 1杨春智1
作者信息
- 1. 深圳市福田区人民医院，广东深圳 518033
- 折叠
摘要
Abstract
OBJECTIVE:To explore the differences of plasma concentration of norvancomycin by HPLC and microbiological method. METHODS:Microbiological method and HPLC were used to detect the plasma concentration of norvancomycin,and clinical test result of both techniques was retrospectively analyzed. RESULTS:There were no significant differences in the plasma concentra-tion of norvancomycin by microbiological method and HPLC(y=0.992 7x+0.155 8,r=0.997 6)(P>0.05). CONCLUSIONS:Both microbiological method and HPLC are more effective and reliable for the plasma concentration detection of norvancomycin. The hospi-tals can choose corresponding method according to their condition when determining plasma concentration of norvancomycin.关键词
高效液相色谱法/微生物法/去甲万古霉素/血药浓度Key words
HPLC/Microbiological method/Norvancomycin/Plasma concentration分类
医药卫生引用本文复制引用
张开礼,李成,李玉珍,杨春智..HPLC法与微生物法测定人血浆中去甲万古霉素浓度的差异比较[J].中国药房,2015,(26):3655-3657,3.
