中国药房Issue(26)：3720-3722,3.DOI:10.6039/j.issn.1001-0408.2015.26.39
临床药师干预前后心胸外科手术预防使用抗菌药物效果评价
Effect Evaluation of Prophylactic Application of Antibiotics in Cardiothoracic Surgery before and after Clini-cal Pharmacist Intervention
余爱荣 1范星 2赵燕 1朱水波 3辛华雯1
作者信息
- 1. 广州军区武汉总医院临床药理科，武汉 430070
- 2. 广州军区武汉总医院肾内科，武汉 430070
- 3. 广州军区武汉总医院心胸外科，武汉 430070
- 折叠
摘要
Abstract
OBJECTIVE:To investigate the effect of clinical pharmacist intervention on prophylactic application of antibiotics in cardiothoracic surgery. METHODS:Medical records of patients underwent cardiothoracic surgery were collected from our hospi-tal during Mar. to Apr. in 2014 (before intervention) and during Jun. to Jul. in 2014 (after intervention). Those were divided into pre-intervention group(n=115)and post-intervention group(n=119). The prophylactic application effect of antibiotics was com-pared before and after intervention. RESULTS:After intervention,the rates of prophylactic application were decreased significantly from 96.5% to 72.3%;the rationality rate of antibiotics selection was improved significantly from 27.9% to 94.2%;The course of prophylactic medication decreased significantly from(5.4±2.8)days to(2.3±1.8)days;the difference had statistical significance before and after intervention(P<0.01). The postoperative infection rate was decreased from 13.0% to 5.9%,the difference had no statistical significance(P=0.074). The average hospitalization time,average drug costs,and average hospitalization expenses were decreased significantly,the difference had statistical significance(P<0.05 or P<0.01). CONCLUSIONS:Clinical pharmacist inter-vention to prophylactic application of antibiotics in cardiothoracic surgery can control the infection effective and guarantee reason-able and safe use of drugs during perioperative period.关键词
心胸外科手术/预防用药/临床药师/干预Key words
Cardiothoracic surgery/Prophylactic application of antibiotics/Clinical pharmacist/Intervention分类
医药卫生引用本文复制引用
余爱荣,范星,赵燕,朱水波,辛华雯..临床药师干预前后心胸外科手术预防使用抗菌药物效果评价[J].中国药房,2015,(26):3720-3722,3.
