中国医药科学2015，Vol.5Issue(14)：141-143,3.
肾小球滤过率估算值及尿蛋白与老年人发生心血管事件的相关性分析
Correlation analysis of estimate of estimated glomerular filtration rate and the elderly cardiovascular events
阮威杰 1赵世腾 2孙少平1
作者信息
- 1. 广东省东莞市塘厦医院内科,广东东莞 523721
- 2. 广东省东莞市塘厦医院口腔科,广东东莞 523721
- 折叠
摘要
Abstract
Objective To detect the relationship between estimated glomerular filtration rate(eGFR)and urinary protein with cardiovascular events in subjects aged 60 years or older.Methods According to the standard,a total of 270 cases for this retrospective prognostic study were drawn from the patient database for routine checkup in Tangxia hospital from January 2008 to December 2009.Based on eGFR,research objects can be divided into decreased renal function group [eGFR<60mL/min 1.73m2] and normal renal function group;At the same time,urinary protein positive group and urinary protein negative group on account of the result of urine routine inspection.Cardiovascular events included cardiovascular death,nonfatal myocardial infarction and nonfatal stroke.Results Mean follow-up (37.0±4.1) months,51 cases of cardiovascular events occurred during follow-up period,including 19 cases of nonfatal stroke,22 cases of nonfatal myocardial infarction and 10 cases of cardiovascular death.Normal renal function group has lower incidence of cardiovascular events than decreased renal function group [10.2%(18/176)vs 35.1%(33/94),x2=9.53, P<0.01].Urinary protein negative group's incidence of cardiovascular events was significantly lower than urinary protein positive group [15.4%(37/241)vs 48.3%(14/29),x2=4.36,P<0.05].Multivariate Cox regression analysis showed that urinary protein and eGFR level is independent risk factor for cardiovascular events.Conclusion Reduced eGFR and presence of proteinuria is independent risk factor for cardiovascular event in subjects aged 60 years or older.关键词
心血管疾病/老年人/估算的肾小球滤过率/蛋白尿Key words
Cardiovascular diseases/Aged/Glomerular filtration rate/Proteinuria分类
医药卫生引用本文复制引用
阮威杰,赵世腾,孙少平..肾小球滤过率估算值及尿蛋白与老年人发生心血管事件的相关性分析[J].中国医药科学,2015,5(14):141-143,3.
