中国医药科学2015，Vol.5Issue(14)：150-152,3.
同型半胱氨酸浓度对脑梗死复发的影响
Effect of homocysteine concentration on the recurrence of cerebral infarction
摘要
Abstract
Objective To investigate the effects of plasma concentrations of homocysteine in patients with recurrent cerebral infarction.Methods 122 cases with high homocysteine in patients with cerebral infarction were randomly divided first episode AB groups,A group of 62 cases,group B 60 cases.Treatment groups are checked before accepting blood sugar,blood lipids, liver function,kidney function,blood.All patients were given conventional treatment according to ischemic stroke treatment guidelines.A group of the homocysteine plasma concentration at 10-15μmol/L,group B control in 10μmol/L or less,both groups with folic acid tablets 5mg/time, 3times/day;B6 20mg/times,3 times/day;B12 25mg/times,2 times/day.After treatment,15 days after the review of plasma homocysteine,hcy control disable anti hcy in plasma levels of the drug required after every subsequent three months later homocysteine 1,to determine the two homocysteine Plasma concentrations of control in their required level,such as the re-emergence of elevated levels of these methods reduced requirements.Recurrence rate of cerebral infarction were observed after 1 year.Results Recurrence rate was 16.13% in group A,group B,the recurrence rate was 5.00%,with a significant difference between the two groups(P<0.05).The two groups in age,gender,showed no significant difference(P>0.05).Two groups of patients before treatment lipids,hypertension,blood glucose,homocysteine,renal function,liver function,hemoglobin showed no significant difference(P>0.05),the two groups were not there in the control process homocysteine serious adverse reactions. Conclusion Plasma homocysteine concentration control in 10μmol/L or less,can significantly reduce the recurrence rate of cerebral infarction,the two groups have significant difference(P<0.05).关键词
同型半胱氨酸/血浆浓度/脑梗死/复发Key words
Homocysteine/Plasma concentration/Cerebral infarction/Recurrence分类
医药卫生引用本文复制引用
王艾,曾广民,张福秋..同型半胱氨酸浓度对脑梗死复发的影响[J].中国医药科学,2015,5(14):150-152,3.基金项目
广东省东莞巿医疗卫生科技计划重点项目(2011105102028). （2011105102028）
