中国医药科学2015，Vol.5Issue(14)：156-158,173,4.
痰脱落细胞涂片结合TCT、痰沉渣琼脂石蜡双包埋片法在肺癌高危人群筛查诊断中的应用
Application of sputum exfoliated cells smear combined with TCT, sputum sediment AGAR paraffin double embedding method in screening and diagnosis of high risk group with lung cancer
摘要
Abstract
Objective To explore the application value of sputum exfoliated cells smear combined with ThinPrep cytology test (TCT) and sputum sediment AGAR paraffin double embedding (APSM) method in screening and diagnosis of high risk group with lung cancer.Methods 189 suspected patients with lung cancer (history of smoking, chest imaging examination positive or negative, clinical symptoms with expectoration and hemoptysis) who were from department of respiration medicine of Nanhai economic development zone People's Hospital, resident's physical examination and factory physical examination from January 2014 to June 2015 were examined with sputum exfoliated cells smear combined with TCT and APSM, and then cytology of TCT and APSM were compared and analyzed.Results In the sputum specimen of 189 suspected patients with lung cancer, 179 patients were confirmed as lung cancer by auto fluorescence bronchoscope (AFB) technology and histopathologic examination of surgical specimens, which accounted for 94.71% (179/189). Examination results of sputum exfoliated cells smear, TCT and APSM were compared (P>0.05). Positive rate of lung cancer cell that tested by sputum exfoliated cells smear and APSM was 97.21%, which was significantly higher than 84.92% that tested by TCT combined with APSM (P<0.05). Conclusion Application of TCT of detachment of cervix cytodiagnosis combined with APSM of pleural and ascitic fluid cytodiagnosis in sputum exfoliated cells can alleviate patients' life pressure from repeated drawing materials and delayed diagnosis to improve positive diagnostic rate and achieve early detection, diagnosis and treatment, so as to decrease the mortality rate of lung cancer due to delayed diagnosis.关键词
痰细胞学/TCT/痰沉渣切片法/肺癌Key words
Sputum cytology/TCT/APSM/Lung cancer分类
医药卫生引用本文复制引用
林淑端,郭智俊,陈石桥,潘啟森,黄倩萍,姜山,吴业辉..痰脱落细胞涂片结合TCT、痰沉渣琼脂石蜡双包埋片法在肺癌高危人群筛查诊断中的应用[J].中国医药科学,2015,5(14):156-158,173,4.基金项目
广东省佛山市卫生和计生局医学科研课题(2015026). （2015026）
