中国医药科学2015，Vol.5Issue(14)：159-161,200,4.
调强放疗联合同期化疗治疗局部晚期鼻咽癌的疗效观察
Observation of curative effect of intensity modulated radiation therapy combined with concurrent chemotherapy in the treatment of locally terminal nasopharynx cancer
摘要
Abstract
Objective To explore the curative effect of intensity modulated radiation therapy (IMRT).Methods Patients with locally terminal nasopharynx cancer who were admitted to our hospital from February 2011 to February 2014 were divided to A group (experimental group, 46 patients) and B group (control group, 40 patients). A group was treated with IMRT and DN (Docetaxel and Nedaplatin) combined with concurrent chemotherapy, and the B group was treated with conventional chemotherapy and DN combined with concurrent chemotherapy. The curative effect, early adverse reactions, advanced adverse reactions of two groups were collected, and the data was analyzed with Chi-square test.ResultsThe difference in curative effect of two groups was not great (P>0.05). In the aspect of early adverse reactions, the mobility of oral mucositis of two groups was 100%. The mobility of Ⅲ level oral mucositis, anemia and leukopenia of A group was significantly lower than that of B group (P<0.05). In the aspect of advanced adverse reactions, the mobility of dry mouth, difficulty in opening mouth and mucosa damage of A group was significantly lower than that of B group (P<0.05).Conclusion IMRT combined with concurrent chemotherapy in the treatment of locally terminal nasopharynx cancer can lower the mobility of early adverse reactions and advanced adverse reactions.关键词
鼻咽癌/调强适形放射治疗/多西他赛/奈达铂Key words
Nasopharynx cancer/IMRT/Docetaxel/Nedaplatin分类
医药卫生引用本文复制引用
黄瑞文,冯庆,柯柳杨,李能平,梁文胜..调强放疗联合同期化疗治疗局部晚期鼻咽癌的疗效观察[J].中国医药科学,2015,5(14):159-161,200,4.基金项目
广东省湛江市第一批非资助科技攻关计划项目(2012C3101050). （2012C3101050）
