摘要
Abstract
Objective To investigate the significance of combined detection of alpha fetoprotein (AFP), alpha fucosidase (AFU), beta 2-microglobulin (β2-m) and hyaluronic acid (HA) in the diagnosis of primary liver cancer. Methods 60 patients with primary liver cancer, 50 cases of other digestive system cancer, 50 patients with hepatic cirrhosis and 60 normal people from 2012 March to 2014 March in our hospital were selected,and serum AFP, AFU, β2-m and HA levels of all patients were detected.Results The levels and positive rates of serum AFP, AFU, β2-m and HA of patients with primary liver cancer were significantly higher than those of patients with other digestive system cancer, liver cirrhosis and normal people, the difference was statiscally significant (P<0.05). The sensitivity and diagnostic accordance rate of combined detection of serum AFU, AFU, β2-m and HA in patients with primary liver cancer were better than those of the single detection, the difference was statiscally significant (P<0.05). Conclusion Combined detection of AFP, AFU, β2-m and HA four tumor markers can improve the sensitivity and diagnosis rate of early primary liver cancer, and provide the reliable reference for early clinical diagnosis and treatment.关键词
原发性肝癌/甲胎蛋白/α-岩藻糖苷酶/β2-微球蛋白/透明质酸Key words
Primary liver cancer/Alpha fetoprotein/Alpha fucosidase/Beta 2-microglobulin/Hyaluronic acid分类
医药卫生
