摘要
Abstract
OBJECTIVE:To study the clinic efficacy of trimetazidine in treatment of coronary heart disease combined with diabetes. METHODS:114 patients with coronary heart disease combined with diabetes from Jan. 2013 to June. 2014 were randomly divided into control group and observation group according to the visiting sequence, and 57 cases in control group underwent conventional treatment, 57 patients in the observation group were treated with the conventional therapy plus trimetazidine treatment, the treatment efficacy was compared in two groups of patients. RESULTS: Before treatment, the two groups of patients in the times of angina attacks, angina duration, blood pressure, blood sugar, heart rate and some other indicators had no significant difference(P>0. 05). After treatment, the attack frequency of patients with angina was significantly reduced, the time of angina was significantly shorten, with significant differences( P <0. 05 ) , and the heart rate, blood pressure and blood sugar had no obvious change (P>0. 05);Also, in observation group, the times of angina was significantly less than that in the control group, the duration of angina was significantly shorter than that in the control group, with significant differences ( P <0. 05 ) . There were no obvious adverse reactions in both groups of patients during treatment. CONCLUSIONS:Trimetazidine in treatment of coronary heart disease combined with diabetes can effectively reduce the times of angina, lower blood sugar, improve the therapeutic efficacy, and can be widely applied in clinical practice.关键词
曲美他嗪/冠心病/糖尿病Key words
Trimetazidine/Coronary heart disease/Diabetes分类
医药卫生