中国医院用药评价与分析2015,Vol.15Issue(8):1082-1084,3.DOI:10.14009/j.issn.1672-2124.2015.08.031
232例药品不良反应报告回顾性分析
Retrospective Analysis of 232 Cases of Adverse Drug Reaction Reports
钟运香 1袁娇 1卢锐辉 1李志平 1罗文娟1
作者信息
- 1. 东莞市第五人民医院药学部,广东东莞 523900
- 折叠
摘要
Abstract
OBJECTIVE:To investigate the occurrence of adverse drug reaction ( ADR ) in 232 cases and its relevant factors,and to provide clinical reference for rational drug use. METHODS: 232 cases of ADR reports were collected to the Monitoring Center of Guangdong Province by the Fifth People's Hospital of Dongguan during 2012-2013,the relevant factors including patients'age and sex,drug varieties, drug form,route of administration,involved organs and( or) systems and clinical manifestation were statistically analyzed. RESULTS: Of the 232 cases,126 cases were male and 106 cases were female,the ratio was 1:1. 189,aged from 2 months to 95 years old. 88 kinds of drugs were involved,leading the list were antimicrobial agents (33kinds,37. 5%),which induced 127 cases of ADR and accounting for 51. 63% of the total 246 cases. Intravenous infusion induced the most cases of ADR, with 175 cases ( accounting for 72. 9% of the total 240 cases) . The main clinical manifestation of ADR was lesions of skin and its accessories,digestive system reactions etc. CONCLUSIONS: The clinic should use antimicrobial rationally,strengthen the monitoring of ADR so as to reduce the occurrence of ADR.关键词
药品不良反应/抗微生物药/合理用药/回顾性分析Key words
Adverse drug reaction/Antimicrobial agents/Rational drug use/Retrospective analysis分类
医药卫生引用本文复制引用
钟运香,袁娇,卢锐辉,李志平,罗文娟..232例药品不良反应报告回顾性分析[J].中国医院用药评价与分析,2015,15(8):1082-1084,3.