中华脑科疾病与康复杂志（电子版）Issue(4)：273-277,5.DOI:10.3877/cma.j.issn.2095-123X.2015.04.015
胎儿酒精综合征的发病机制研究进展
Research progress of pathogenesis of fetal alcohol syndrome
摘要
Abstract
Fetal alcohol syndrome has lots of disastrous effect on the development of fetal craniofacial ,central nervous system and growing ,causing heavy financial burden and mental stress shouldered by individuals,families and the society.Unfortunately,the pathogenesis of the disease is still not so clear that it is hard to do targeted therapies .We reviewed the recent researches on the pathogenesis of fetal alcohol syndrome,mainly showing the effect of epigenetics ,neuro-immune,inward rectifier potassium channel Kir 2.1 and oxidative stress on it and presenting other relative pathogenesis briefly , such as apoptosis theory and neurotransmitter′s influence on fetal alcohol syndrome .Through comprehensive analysis ,we found that there were indeed fruitful researches on the pathogenesis of fetal alcohol syndrome which were not mature ,such as the precise role of epigenetics ,neuro-immune,inward rectifier potassium channel Kir 2.1 in the development of fetal alcohol syndrome is unknown ,so was the specific process of the imbalance of the redox state in cells caused by the alcohol ,which deserved further researches .关键词
胎儿酒精综合征/神经免疫调节/发病机制/表观遗传学/Kir2.1/氧化应激Key words
Fetal alcohol syndrome/Neuroimmunomodulation/Pathogenesis/Epigenetics/Kir2.1/Oxidative stress引用本文复制引用
廖欢,李艺,彭英..胎儿酒精综合征的发病机制研究进展[J].中华脑科疾病与康复杂志（电子版）,2015,(4):273-277,5.基金项目
国家自然科学基金青年科学基金项目 （）
