安徽医科大学学报2015，Vol.50Issue(10)：1486-1488,3.
337例胎儿超声软指标阳性染色体结果分析
Analysis on chromosomal outcome of ultrasound soft marker of 337 fetuses
摘要
Abstract
Objective To analyze the chromosome karyotype of abnormal ultrasound soft markers( USMs) and dis-cuss the relationship betweeen the USMs and chromosomal abnormality. Methods Selecting the 337 pregnant women who did the prenatal diagnosis with the USMs,recording the chromosome karyotype of fetuses and doing the retrospective study. The research subjects were divided into three groups,including the only USMs group( group A, 186 cases;containing only one USMs,group A1,150 cases;one more USMs,group A2,36 cases),the USMs merging the eldly pregnant women or high risk of Downs' screening( group B,82 cases) ,the USMs merging the other abnor-mality( group C,69 cases) ,and analyzing the relationship with chromosomal abnormality. Results The incidence of chromosomal abnormalities between A1 and A2 was not statistically significant, and the A and B were the same, however the incidence of chromosomal abnormalities between A and C was statistically significant ( P <0. 05 ) . Conclusion The USMs may improve the risk of chromosomal abnormality,assessing the practical value correctly to decline the unnecessarily invasive prenatal diagnosis. Nevertheless,USMs merging other structural abnormalities can continue the pregnancy under the condition of the normal chromosome karyotype.关键词
超声软指标/染色体核型分析/产前诊断Key words
ultrasound soft marker/karyotype analysis/prenatal diagnosis分类
医药卫生引用本文复制引用
杨琴,丛林,袁静,方慧琴,陈薇..337例胎儿超声软指标阳性染色体结果分析[J].安徽医科大学学报,2015,50(10):1486-1488,3.基金项目
安徽省自然科学基金(编号:1208085MH172) （编号:1208085MH172）
安徽高校省级自然科学研究项目(编号:KJ2011Z215) （编号:KJ2011Z215）
