北京中医药大学学报Issue(9)：635-640,6.DOI:10.3969/j.issn.1006-2157.2015.09.012
真实世界下不同中医证候要素慢性心力衰竭患者远期预后的比较分析
Comparison of long-term prognosis of chronic heart failure patients with different TCM syndrome elements in real world
摘要
Abstract
Objective To compare the long-term prognosis of chronic heart failure ( CHF) patients with different TCM syndrome elements of phlegm stagnation, qi deficiency, yin deficiency, blood statis and yang deficiency.Methods Subjects were 191 CHF inpatients in Guang’ anmen Hospital from January 2006 to August 2011. The clinic information of the patients were collected, including general information, incidence and TCM syndrome elements.After discharging from the hospital, all the patients were visited in outpatient or followed up by telephone for years to get the occurrence and duration of all-cause mortality.Results The long-term prognosis of CHF patients with TCM syndromes ranked from the best to the worst: phlegm stagnation, qi deficiency, yin deficiency, blood stasis and yang deficiency (P<0.01).The prognosis of patients with syndrome of phlegm stagnation was better than those without phlegm stagnation ( P=0.017);patients with syndrome of qi deficiency had a better prognosis than those without qi deficiency ( P=0 .011 ); there was no significant difference in patients with or without yin deficiency (P=0.633); the overall prognosis of blood stasis patients showed no significant difference with non blood-stasis patients (P=0.182), but went worse from the 500th day;the prognosis of patients with syndrome of yang deficiency was worse than patients without yang deficiency ( P =0 .002 ) . Conclusion The long-term prognosis of CHF patients is definitely poor.The prognosis of CHF patients with different TCM syndromes showed striking difference.Syndrome of qi deficiency and syndrome of phlegm stagnation would be ordinary in early stage of CHF, and syndrome of yin deficiency played a role through the whole progression of CHF.The effect of syndrome of blood stasis could be associated with CHF disease progression, and the prognosis of patients with blood statis was worse.The syndrome of yang deficiency would be the main syndrome in late stage.关键词
慢性心力衰竭/中医证候/预后Key words
chronic heart failure/long-term prognosis/TCM syndrome elements分类
医药卫生引用本文复制引用
徐峥,张并璇,宋庆桥,田瑜,黄巍..真实世界下不同中医证候要素慢性心力衰竭患者远期预后的比较分析[J].北京中医药大学学报,2015,(9):635-640,6.基金项目
国家自然科学基金项目 （）
