国际医药卫生导报2015，Vol.21Issue(18)：2712-2714,3.DOI:10.3760/cma.j.issn.1007-1245.2015.18.019
晚期肺癌患者血浆N-端脑利钠肽前体水平变化及临床分析
The change and clinical analysis of the level of plasma N-terminal pro-brain natriuretic peptide in advanced lung cancer patients
摘要
Abstract
Objective To explore the change of the level of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) in advanced lung cancer patients and its clinical significance.Methods 40 cases of advanced lung cancer were selected as observation group,and 28 cases of early lung cancer were selected as control group.At the 2nd,9th day after hospitalization,assessed cardiac functional grading,tested the level of plasma NT-proBNP and LVEF,and compared the differences of above indexes at different time points.Results There was no statistically significant difference in cardiac functional grading between two groups at the 2nd day after hospitalization (P＞0.05);at the 9th day after hospitalization,the incidence of heart failure in observation group was 15.0％(6/40),significantly higher than that in control group (P＜0.05).There were statistically significant differences in the level of NT-proBNP between two groups at the 2nd,9th day after hospitalization (P＜0.05).The level of NT-proBNP in observation group at the 9th day after hospitalization was significantly higher than that at the 2nd day after hospitalization (P＜0.01).Conclusion NT-proBNP is very sensitive in predicting cardiac complications of advanced lung cancer,and we should attach importance to its clinical significance.关键词
晚期肺癌/N-端脑利钠肽前体/心力衰竭/心功能分级Key words
Advanced lung cancer/N-terminal pro-brain natriuretic peptide/Heart failure/Cardiac functional grading引用本文复制引用
李传文,魏庆娟..晚期肺癌患者血浆N-端脑利钠肽前体水平变化及临床分析[J].国际医药卫生导报,2015,21(18):2712-2714,3.
