国际病理科学与临床杂志Issue(9)：1627-1631,5.DOI:10.3978/j.issn.2095-6959.2015.09.010
RRAD在乳腺癌中的表达及其临床意义
RRAD expression and its clinical significance in breast cancer
曹晓丽 1孙荣能1
作者信息
- 1. 安徽省芜湖市第二人民医院乳腺外科，安徽芜湖241000
- 折叠
摘要
Abstract
Objective:To study the expression of Ras-related associated with diabetes (RARD) and its clinical signiifcance in breast cancer. Methods:RRAD expression was tested with Real-time PCR and Western blot in 74 cases of breast cancer patients’ (which were female patients with age from 25 to 65 years) tissues, which were treated in Department of Breast Surgery of the Wuhu No.2 People’s Hospital from Jan 2013 to Jan 2014. hTe correlation between RRAD expression and age, tumor size, tumor differentiation and lymph node metastasis clinical parameters were evaluated. Results:RRAD expression levels were increased with the TNM staging of breast cancer rises (P<0.05);the difference between RARD expression and age was not statistically signiifcant (P>0.05), RRAD was positively correlated with tumor size, tumor differentiation and lymph node metastasis (P<0.05). Conclusion:RARD is over expressed in breast cancer tissues and closely related to tumor progression, RARD is possibly an important target for the prevention and control of breast cancer.关键词
乳腺癌/RRAD/远处转移Key words
breast cancer/RARD/distant metastasis引用本文复制引用
曹晓丽,孙荣能..RRAD在乳腺癌中的表达及其临床意义[J].国际病理科学与临床杂志,2015,(9):1627-1631,5.
