临床与病理杂志Issue(9)：1643-1647,5.DOI:10.3978/j.issn.2095-6959.2015.09.013
15例妊娠期急性脂肪肝的早期诊断及治疗
Early diagnosis and management of 15 cases of acute fatty liver of pregnancy
王晓艳 1陶建英1
作者信息
- 1. 苏州市立医院，苏州市母子医疗保健中心妇产科，江苏苏州215004
- 折叠
摘要
Abstract
Objective:To explore the early diagnosis and management of acute fatty liver of pregnancy (AFLP) so as to improve maternal and fetal survival. Methods:The clinical findings and outcomes of pregnancy were retrospectively analyzed in 15 patients with AFLP in this hospital from January 2011 to January 2015. Results:A total of 15 AFLP manifested in the third trimester, 12 of whom were nulliparas and 3 of whom were multiparas;13 of whom were singleton pregnancy and 2 of whom were twin pregnancy. There were total 17 fetuses, 12 of whom were males and 5 of whom were females. There were 7 patients with hypertension, 9 with lower blood glucose levels, and 13 with symptoms, including nausea, vomiting and anorexia. hTe duration from admission to fetal delivery was 0.5~21.5 hours. All patients preserved their uteri, with 14 patients ending the pregnancy with cesarean section and 1 with vaginal delivery. Two patients were complicated with postpartum hemorrhage. hTere was no maternal death. Fourteen newborns were normal, 1 was asphyxia and 3 were fetal deaths. Conclusion:hTe key to improving the prognosis of both mothers and fetuses is to make early diagnosis and to end the pregnancy timely. Multimodality therapy with the help of multiple departments and the artiifcial liver support system timely are effcient in reducing the maternal mortality.关键词
妊娠期急性脂肪肝/诊断/治疗/人工肝支持系统Key words
acute fatty liver of pregnancy/diagnosis/management/artiifcial liver support system引用本文复制引用
王晓艳,陶建英..15例妊娠期急性脂肪肝的早期诊断及治疗[J].临床与病理杂志,2015,(9):1643-1647,5.
