解放军医学院学报2015，Vol.36Issue(9)：892-895,4.DOI:10.3969/j.issn.2095-5227.2015.09.010
实时剪切波弹性成像在甲状腺微小癌诊断中的应用
Application of real-time shear wave elastography in diagnosis of thyroid micro carcinoma
摘要
Abstract
Objective To explore the value of real-time shear wave elastography (SWE) in diagnosis of thyroid micro carcinoma (TMC).Methods Out-patients with thyroid small nodule suspected malignant who underwent ultrasound examination from June 2014 to December 2014 in our hospital were enrolled in this study. Sixty-seven nodules (≤1.0 cm) in 62 patients were examined by SWE to get the Young's modulus. Pathologic results were served as the golden standard to construct the ROC curves, and the value of SWE in diagnosis of TMC was evaluated.Results Of the 67 nodules, 37 were TMC and 30 were benign. The maximum and mean elasticity value of TMC were (58.47±31.51) kPa and (41.58±23.36) kPa, while the maximum and mean elasticity value of the micro benign nodules were (26.94±14.31) kPa and (18.03±10.83) kPa, which weresignificantly lower than those of TMC (t = 5.063,P = 0.000;t = 4.591,P=0.000); Taking 40 kPa as the threshold of the maximum elasticity value, the sensitivity was 84.3% and the specificity was 91.2%. Taking 35 kPa as the threshold of the mean elasticity value, the sensitivity was 80.0% and the specificity was 94.2%. The area under the ROC curve of the maximum, mean elasticity value was 0.942, 0.923 (P<0.05).Conclusion SWE can be used for the quantitative determination of thyroid micro carcinoma hardness, and it is helpful in differential diagnosis of thyroid micro carcinoma.关键词
超声检查/甲状腺微小癌/剪切波弹性成像Key words
ultrasonography/thyroid microcarcinoma/shear wave elastography分类
医药卫生引用本文复制引用
李建如,罗渝昆,李岩密,温泉,张雁,张艳,何萍..实时剪切波弹性成像在甲状腺微小癌诊断中的应用[J].解放军医学院学报,2015,36(9):892-895,4.基金项目
北京市自然科学基金项目(7152137) Supported by the Natural Science Foundation of Beijing(81471681) （7152137）
