临床误诊误治Issue(9)：13-16,4.DOI:10.3969/j.issn.1002-3429.2015.09.007
POEMS综合征长期误诊并文献复习
One Long Time Misdiagnosed Case of POEMS Syndrome and Literature Review
吴婷婷 1章必成 1冉启杰 2邓文娟 1饶智国 1高建飞1
作者信息
- 1. 430070 武汉，广州军区武汉总医院肿瘤科
- 2. 430070 武汉，广州军区武汉总医院血液科
- 折叠
摘要
Abstract
Objective To explore the clinical characteristics and diagnosis criteria of POEMS syndrome, so as to re-duce the misdiagnosis and mistherapy rates. Methods Clinical data of one long time misdiagnosed case of POEMS syndrome was analyzed retrospectively. Meanwhile, the related literature was reviewed. Results The patient was admitted for intermit-tent tachypnea for over 2 years, acroanesthesia of lower limbs and costopathy for 9 months, skin itching for 7 months, limping for 3 months. At first, he was diagnosed as having diabetes mellitus, tuberculous pleuritis by laboratory tests, CT, bone scan-ning and pleural pathology in other hospitals. Then he was diagnosed as having chronic urticaria, skin pruritus for itchy skin, and metastatic adenocarcinoma ( to be excluded) for repeated hydrothorax. Finally, the patient was diagnosed as having PO-EMS syndrome in our hospital by the combination of PET-CT, bone lesions biopsy, bone marrow aspiration and immunohisto-chemisty, and underwent chemotherapy and radiotherapy, and the patient was in a remission. Conclusion POEMS syndrome is a rare, independent monoclonal plasma cell disorder, which has the clinical manifestations relaled to many systems and the therapeutic methods including chemotherapy and radiotherapy. Strengthening the awareness of this disease is helpful to avoid the misdiagnosis and mistherapy.关键词
POEMS综合征/浆细胞瘤/误诊/糖尿病/胸膜炎/荨麻疹/腺癌Key words
POEMS syndrome/Plasmacytoma/Misdinogsis/Diabetes mellitus/Pleurisy/Urticaria/Adenocarcinoma分类
医药卫生引用本文复制引用
吴婷婷,章必成,冉启杰,邓文娟,饶智国,高建飞..POEMS综合征长期误诊并文献复习[J].临床误诊误治,2015,(9):13-16,4.
