国际眼科杂志Issue(9)：1671-1674,4.DOI:10.3980/j.issn.1672-5123.2015.9.53
鼻咽癌放疗术后眼部并发症的临床分析
Clinical study on ocular complications subsequent to radiotherapy of nasopharyngeal carcinoma
摘要
Abstract
AIM:To investigate the clinical features, characteristics of fundus fluorescein angiography ( FFA ) indocyanine green angiography ( ICGA ) , risk factors, diagnostic methods and therapies of ocular complications subsequent to radiotherapy of nasopharyngeal carcinoma ( NPC) . <br> METHODS: Thirty - three patients ( 63 eyes ) with hypopsia subsequent to radiotherapy of NPC admitted to Chenzhou No. 1 People's Hospital from March 2007 to March 2012 were investigated retrospectively. <br> RESULTS:All cases manifested as progressive, painless hypopsia in binocular or monocular. Fifty - six eyes received FFA and ICGA. Forty - eight eyes showed radiation retinopathy, including 2 eyes with central retinal artery occlusion, 3 eyes with central retinal vein occlusion, 2 eyes with retinal pigment epithelial changes, 1 eye with epiretinal membrane and the remaining 40 eyes appeared cotton woolspots at posterior pole and hemorrhage. Thirty-six eyes manifested as radiation optic neuropathy, of them, optic border of 27 was clear, and that of 9 eyes was unclear. Two eyes were typical macular choroidal neovascularization ( CNV) , 1 eye was choroidal metastasis, 4 eyes presented choroidal abnormal circulation, 2 eyes displayed anterior uveitis and 7 eyes manifested vitreous hemorrage. <br> CONCLUSION: Ocular complications subsequent to radiotherapy of NPC are complicated and diverse, the most common damage is radiation retinopathy and radiation optic neuropathy, whereas the small number of them are characterized by macular CNV, arterio-venous obstruction and abnormal choroid.关键词
鼻咽癌/放射治疗/眼部并发症Key words
nasopharyngeal carcinoma/radiotherapy/ocular complication引用本文复制引用
刘茹,邝国平,谢丽莲,田涛,彭婧利..鼻咽癌放疗术后眼部并发症的临床分析[J].国际眼科杂志,2015,(9):1671-1674,4.基金项目
郴州市第一人民医院院内课题资助(No. N2014-009) （No. N2014-009）
