器官移植Issue(5)：331-334,339,5.DOI:10.3969/j.issn.1674-7445.2015.05.011
活体肾移植供肾肾小球滤过率对术后移植肾功能恢复的影响
Influence of glomerular filtration rate of living donor on recovery of graft function after transplantation
摘要
Abstract
Objective To investigate the influence of glomerular filtration rate (GFR)of living donor on recovery of graft function after transplantation.Methods Clinical data of 108 pairs of donors and recipients undergoing living donor renal transplantation at the Organ Transplantation Center of First Affiliated Hospital of Kunming Medical University from 2009 to 2013 were retrospectively studied.The objects were divided into G1 group (GFR <40 ml/min),G2 group(GFR 40 ~45 ml/min),G3 group(GFR 46 ~50 ml/min)and G4 group (GFR >50 ml/min)according to GFR of the donor kidneys.Changes in serum creatinine (Scr)at 1 week,2 weeks,3 weeks,1 month,3 months,6 months and 1 year after transplantation as well as survival conditions of patient and kidney within 1 year after transplantation of each group were compared.Results Compared with G1 group,Scr at 2 weeks,3 weeks,1 month after transplantation was lower in G2 group,G3 group and G4 group,and the difference had statistical significance (all in P <0.05).As for survival conditions of patient and kidney within 1 year after transplantation,one patient in G1 group developed graft failure due to hyperacute rejection and one patient in G1 group died of severe pulmonary infection.One patient in G2 group developed graft failure due to acute rejection.One patient in G3 group died of severe pulmonary infection.One patient in G4 group died of severe pulmonary infection. Other patients and grafts survived during the follow-up.Conclusions Low GFR of living kidney donor has certain influence on recovery of graft function in the early stage (within one month)after renal transplantation.关键词
肾移植/活体供体/肾功能/肾小球滤过率Key words
Renal transplantation/Living donor/Renal function/Glomerular filtration rate分类
医药卫生引用本文复制引用
苏子庭,李珍,曾仲,刘涛,段键,黄汉飞,林杰..活体肾移植供肾肾小球滤过率对术后移植肾功能恢复的影响[J].器官移植,2015,(5):331-334,339,5.基金项目
云南省教育厅科学研究基金项目（2014Y150）；云南省卫生科技计划项目（2012ws0019）；云南省教育厅科学研究基金项目 （）
