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三种方法联合检测在非 HIV 感染儿童马尔尼菲青霉病的临床应用

何维娜 苏丹虹 吕东月 丁华 华建江 何玥 梁鸿

现代检验医学杂志Issue(4):87-90,4.
现代检验医学杂志Issue(4):87-90,4.DOI:10.3969/j.issn.1671-7414.2015.04.024

三种方法联合检测在非 HIV 感染儿童马尔尼菲青霉病的临床应用

Clinical Applification of Combined Detection of Pencilliosis Marneffei in a Non-HIV-infected Child

何维娜 1苏丹虹 2吕东月 1丁华 1华建江 1何玥 1梁鸿1

作者信息

  • 1. 广州医科大学附属深圳沙井医院,广东深圳 518104
  • 2. 广州医科大学附属第一医院,广州 518102
  • 折叠

摘要

Abstract

Objective To study the diagnostic value of pencilliosis marneffei (PM)in a non-HIV-infected child with the com-bined detection of aspergillosis galactomannan,fungus Glucan(1-3)-β-D and boold culuture.Methods The venous blood specimen from the child was collected for the quantified detection of aspergillosis galactomannan,fungus Glucan(1-3)-β-D. The growth and colonial morphology of fungus was inspected with the positive blood culture and the characteristics of fun-gus smear were observed under microscope.Results The result of aspergillosis galactomannan was 14.45 μg/L and fungus Glucan (1-3)-β-D 77.14 pg/ml.Penicillium marnrffei was identified using blood culture.It was mycelia form under 25℃ and the salouraud medium produced water soluble claret-red pigment produced.It was mycelia form under 35℃ and the colony was gyri creases,the characteristic broom-like hypha and separation hypha could be found under microscope.Conclusion It is effective for the early diagnosis and therapy of PM with the combination detection of aspergillosis galactomannan,fungus Glucan (1-3)-β-D and boold culuture and have better clinical diagnosis value.

关键词

非HIV感染/儿童/马尔尼菲青霉病/联合检测

Key words

non-HIV-infection/child/pencilliosis marneffei/combined detection

分类

医药卫生

引用本文复制引用

何维娜,苏丹虹,吕东月,丁华,华建江,何玥,梁鸿..三种方法联合检测在非 HIV 感染儿童马尔尼菲青霉病的临床应用[J].现代检验医学杂志,2015,(4):87-90,4.

现代检验医学杂志

OACSTPCD

1671-7414

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