现代检验医学杂志Issue(4)：111-114,4.DOI:10.3969/j.issn.1671-7414.2015.04.032
采用不同血管通路采集自体外周血造血干细胞的安全性及有效性评估
Safety and Efficacy of Adopting Different Vascular Access During Autologous Peripheral Blood Stem Cells Collection
陈瑾 1郭彩利 1孙春红 1刘芳 1王艳 1王晓宁1
作者信息
- 1. 西安交通大学第一附属医院，西安 710061
- 折叠
摘要
Abstract
Objective To assess the safety and efficacy of adopting different vascular access during autologous peripheral blood stem cells collection.Methods 87 patients received autologous peripheral blood stem cells collection were divided into two groups:One was peripheral vein harvesting group (43 cases),which used the 16G disposable fistula needle for autolo-gous peripheral blood stem cell collection and the other central venous harvesting group (44 cases),which used double cavity of femoral vein catheter for autologous peripheral blood stem cell collection.The observation indicators included venous ac-cesses,collection efficiency,patient tolerance,the number of mononuclear cell and CD34 positive cells.Results The numbers of mononuclear cells and CD34 positive cells in two groups were all above the standard and there was no significant differ-ence (P >0.05).However,the success of venous accesses,the efficiency smooth of collection and-patient tolerance were bet-ter in double cavity of femoral vein catheter group (P <0.05).Conclusion Harvesting the autologous peripheral blood stem cell through central venous by using double cavity of femoral vein catheter had the advantages as follows:high success rate of puncture,acquisition smoothly and reducing the suffering extent of the patients,and also it did not affect the acquisition effi-ciency and effectiveness.关键词
造血干细胞采集/双腔股静脉置管/单个核细胞Key words
stem cell collection/double cavity of femoral vein catheter/mononuclear cells分类
医药卫生引用本文复制引用
陈瑾,郭彩利,孙春红,刘芳,王艳,王晓宁..采用不同血管通路采集自体外周血造血干细胞的安全性及有效性评估[J].现代检验医学杂志,2015,(4):111-114,4.
