摘要
Abstract
Objective To observe the tiotroPium Powder inhaler in the maintenance treatment of COPD Patients to imProve lung function, the quality of life and reduce the role of the acute exacerbation. Methods 360 cases of Patients in the hosPital with chronic obstruc-tive Pulmonary disease were randomly divided into the control grouP and the observation grouP, 180 cases in each grouP. Both grouPs were given conventional anti-inflammatory, antitussive, exPectorant, oxygen and other treatment, if acute exacerbation aPPeared, the salbu-tamol aerosol agent for emergency treatment was aPPlied. The control grouP were treated with iPratroPium bromide aerosol inhalation ( inhaled 5 mg/time, tid. ) , the observation grouP were treated with tiotroPium Powder inhalation ( inhaled 1 Pill/time, qd. ) . Two grouPs were treated for 12 weeks as 1 course of treatment. Results ComPared with before treatment, Pulmonary function, 6 MWD and dysPnea index scores of the two grouPs after 6 and 12 weeks of treatment were imProved, the observation grouP imProved more significantly than the control grouP ( P < 0. 05 );the acute exacerbation incidence of the observation grouP was significantly lower than that of the control grouP ( P < 0. 05 ) . The adverse reactions of the two grouPs were mild and had no significant difference between the grouPs ( P >0. 05 ) . Conclusion TiotroPium Powder inhal in the maintenance treatment of Patients with COPD can obviously imProve the lung func-tion, reduce the airway and breathing difficulties, imProve the quality of life, has the good function to reduce the risk of Patients with a-cute aggravating, and is worth of clinical Promotion.关键词
噻托溴铵粉雾剂/慢性阻塞性肺疾病/急性加重/临床疗效Key words
tiotroPium Powder inhal/chronic obstructive Pulmonary disease/acute exacerbation/clinical effcacy分类
医药卫生
