中国药业Issue(17)：100-100,101,2.
腺苷钴胺辅助治疗三叉神经痛60例
Clinical Efficacy and Safety of Adding Adenosine Cobaltamine on Trigeminal Neuralgia in 60 Cases
王明远 1王成凤 1李红燕1
作者信息
- 1. 新疆维吾尔自治区人民医院，新疆 乌鲁木齐 830001
- 折叠
摘要
Abstract
Objective To observe the clinical curative effect and safety of adenosine cobaltamine in treating of trigeminal neuralgia. Methods 120 Patients of Primary trigeminal neuralgia in the hosPital between January 2012 and January 2015 were randomly divided into the observation grouP and the control grouP,60 cases in each grouP. The control grouP were given carbamazePine treatment,and the observation grouP were combined with adenosine cobaltamine injections based on the above treatment, for 4 weeks. Results The total effective rate of the observation grouP was 95. 00%, which was higher than 81. 67% of the control grouP ( P < 0. 05 );comPared with before treatment, the Pain on quality of life scores of two grouPs after treatment were both decreased ( P < 0. 05 );4 weeks after treat-ment, the influence of Pain on the quality of life in the observation grouP was significantly lower than the control grouP ( P < 0. 05 );the incidence of adverse reactions in the two grouPs had no statistical difference ( P > 0. 05 );in the follow-uP after 6 months, the re-currence in the observation grouP were 3 Patients ( 5. 00%) which is significanfly lower than 11 Patients ( 18. 33%) in the control grouP ( P < 0. 05 ) . Conclusion Adding adenosine cobaltamine on the conventional treatment in Patients with Primary trigeminal neuralgia treated has clear clinical curative effect, can effectively relieve Pain, imProve the Patient's quality of life with good safety and low reoc-curence rate, and is worth of clinical Promotion.关键词
腺苷钴胺/三叉神经痛/临床疗效/安全性Key words
adenosine cobaltamine/trigeminal neuralgia/clinical curative effect/safety分类
医药卫生引用本文复制引用
王明远,王成凤,李红燕..腺苷钴胺辅助治疗三叉神经痛60例[J].中国药业,2015,(17):100-100,101,2.
