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首页|期刊导航|中国药业|海藻酸钠微球血管栓塞剂治疗多发性子宫肌瘤100例疗效及安全性评价

海藻酸钠微球血管栓塞剂治疗多发性子宫肌瘤100例疗效及安全性评价

李召梅 袁秀红

中国药业Issue(18):45-46,47,3.
中国药业Issue(18):45-46,47,3.

海藻酸钠微球血管栓塞剂治疗多发性子宫肌瘤100例疗效及安全性评价

Efficacy and Safety of Sodium Alginate Uterine Artery Embolization for Treating Multiple Fibroid in 100 Cases

李召梅 1袁秀红2

作者信息

  • 1. 陕西省延安市富县人民医院,陕西 延安 727500
  • 2. 延安大学附属医院,陕西 延安 716000
  • 折叠

摘要

Abstract

Objective To observe the clinical efficacy and safety of sodium alginate uterine artery embolization for treating multiple fi-broid. Methods Totally 200 patients admitted to the hospital were divided into the control group and the observation group according to the random number table method,100 cases in each group. The control group was given conventional surgical treatment,the observa-tion group was given sodium alginate uterine artery embolization. Results After 3,6 months of treatment,the total effective rate of the observation group was significantly higher than that of the control group( P ﹤ 0. 05);the shrink of uterine fibroid volume of the obser-vation group was significantly better than that of the control group( P ﹤ 0. 05);the E2,FSH,LH changes of the observation group were significantly lower than those of the control group( P ﹤ 0. 05);the APC between the two groups had no significant difference before treatment,the control group showed no significant difference after 3 months of treatment,and was significantly lower after 6 months of treatment than that before treatment( P ﹤ 0. 05);there was no statistically significant difference of APC in the observation group after 3,6 months of treatment( P ﹥ 0. 05). The incidence rate of menopausal symptoms of the observation group was 6. 67%,which was sig-nificantly less than 27. 50% of the control group (χ2=15. 272 7,P=0. 000 1). There was no significant difference in the incidence rate of adverse reactions between the two groups( P ﹥ 0. 05). Conclusion Sodium alginate uterine artery embolization in treating multi-ple fibroids can effectively reduce the volume of uterine fibroids,improve the therapeutic effect in the near future,reduce the periopera-tive incidence of menopausal symptoms,contribute to the recovery of ovarian function,with remarkable clinical effect.

关键词

海藻酸钠/微球栓塞剂/多发性子宫肌瘤/卵巢功能/安全性

Key words

sodiunl alginate/uterine artery embolization/multiple fibroid/ovarian function/safety

分类

医药卫生

引用本文复制引用

李召梅,袁秀红..海藻酸钠微球血管栓塞剂治疗多发性子宫肌瘤100例疗效及安全性评价[J].中国药业,2015,(18):45-46,47,3.

中国药业

1006-4931

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