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二乙酰氨乙酸乙二胺治疗肝硬化消化道出血52例疗效评价

徐凤华 董月华 薛净 李明

中国药业Issue(18):49-50,2.
中国药业Issue(18):49-50,2.

二乙酰氨乙酸乙二胺治疗肝硬化消化道出血52例疗效评价

Clinical Efficacy of Ethylenediamine Diaceturate for Treating Liver Cirrhosis with Gastroin-testinal Hemorrhage in 52 Cases

徐凤华 1董月华 1薛净 1李明1

作者信息

  • 1. 武警北京总队医院,北京 100027
  • 折叠

摘要

Abstract

Objective To investigate the efficacy of ethylenediamine diaceturate in treating liver cirrhosis with gastrointestinal hemor-rhage. Methods Totally 104 patients were randomly divided into the control group and the observation group,52 cases in each group. The control groups used octreotide hemostasis treatment on the basis of routine internal medicine treatment,the observation group were given ethylenediamine diaceturate to replace the hemostatic drug,and the other treatment remained unchanged. Results After treatment,the total effective rate of the observation group was 73. 08%,which was obviously higher than 59. 61% of the control group ( P ﹤ 0. 05 );the hemoglobin and pulse rate of the two groups were significantly decreased( P ﹤ 0. 05),but there was no significant difference between the two( P ﹥ 0. 05);the recurrence bleeding rate of the observation group was 5. 26%,which was significantly lower than 12. 90% of the control group( P ﹤ 0. 05);the coagulation function and platelet function in the observation group improved signifi-cantly( P ﹤ 0. 05),and the control group showed no significant change( P ﹥ 0. 05). The adverse reactions of the two groups had no significant difference. Conclusion Ethylenediamine diaceturate in treating liver cirrhosis with upper gastrointestinal hemorrhage has exact effect,and good safety and can significantly reduce the recurrence rate after patients stopped bleeding.

关键词

二乙酰氨乙酸乙二胺/肝硬化/消化道出血/复发

Key words

ethylenediamine diaceturate/liver cirrhosis/gastrointestinal hemorrhage/recurrence

分类

医药卫生

引用本文复制引用

徐凤华,董月华,薛净,李明..二乙酰氨乙酸乙二胺治疗肝硬化消化道出血52例疗效评价[J].中国药业,2015,(18):49-50,2.

中国药业

1006-4931

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