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青蒿素类抗疟制剂研究概述

沈硕 刘淑芝 杜茂波

中国中医药信息杂志Issue(10):125-128,4.
中国中医药信息杂志Issue(10):125-128,4.DOI:10.3969/j.issn.1005-5304.2015.10.039

青蒿素类抗疟制剂研究概述

Research Progress of Artemisinins-based Antimalarial Agents

沈硕 1刘淑芝 1杜茂波1

作者信息

  • 1. 中国中医科学院中药研究所,北京 100700
  • 折叠

摘要

Abstract

Artemisinin is the antimalarial active ingredient, which is discovered by Chinese scientists in 1970s. The chemical structure of artemisinin is modified or altered to obtain a series of analogues to satisfy the medication requirements. According to the physicochemical properties of medicines and actual clinical necessities, the preparations of artemisinins are developed and the common preparations include tablet, suppository, injection, etc.. With the developing of technology, researchers have conducted a large number of studies on the artemisinins nanoparticles injection, transdermal drug delivery systems, mucosal drug delivery systems and etc. This article systematically collected and discussed the recent studies on the antimalarial preparations of artemisinins in line with different administration routes.

关键词

青蒿素/疟疾/抗疟制剂/综述

Key words

artemisinin/malaria/antimalarial agent/review

分类

医药卫生

引用本文复制引用

沈硕,刘淑芝,杜茂波..青蒿素类抗疟制剂研究概述[J].中国中医药信息杂志,2015,(10):125-128,4.

基金项目

中国博士后科学基金(2013M541159);中国中医科学院基本科研业务费自主选题项目(ZZ0608) (2013M541159)

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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