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2型糖尿病患者胰岛素抵抗与血小板抵抗的关系

刘远波 周伯荣 张莹 王融 谢毅娟 孟栋栋

广东医学Issue(16):2526-2529,4.
广东医学Issue(16):2526-2529,4.

2型糖尿病患者胰岛素抵抗与血小板抵抗的关系

The correlation between insulin resistance and platelet resistance

刘远波 1周伯荣 2张莹 3王融 4谢毅娟 3孟栋栋3

作者信息

  • 1. 广东省惠州市中大惠亚医院神经内科 516081
  • 2. 广州医科大学附属第三医院 神经内科
  • 3. 广州医科大学附属第三医院 内分泌科
  • 4. 广州医科大学附属第三医院检验科 广州 510150
  • 折叠

摘要

Abstract

Objective To investigate the correlation between insulin resistance ( IR) in type 2 diabetic patients with aspirin resistance ( AR) and clopidogrel resistance ( CR) .Methods Eighty-one cases of non -insulin-resistant (NIR) were selected as normal controls and divided into NIR aspirin group (NIR+AS, n=28) and NIR clopidogrel group (NIR+CL, n=43);while 80 cases of IR patients were selected and divided into IR aspirin group (IR+AS, n=38) and IR clopidogrel group (IR+CL, n=42).The rate of platelet aggregation (RPA) was examined on baseline and one week after medication for analysis .Results Four cases (10.53%) of AR were found in NIR+AS group, while 11 cases (28.95%) found in IR+AS group, with significant difference (P<0.05).Six cases (13.95%) of CR were re-vealed in NIR+CL group, while 14 cases (33.33%) revealed in IR+CL group, with significant difference (P<0.05). Conclusion IR is correlated with platelet resistance .

关键词

胰岛素抵抗/血小板抵抗/阿司匹林抵抗/氯吡格雷抵抗

Key words

insulin resistance/platelet resistance/aspirin resistance/clopidogrel resistance

引用本文复制引用

刘远波,周伯荣,张莹,王融,谢毅娟,孟栋栋..2型糖尿病患者胰岛素抵抗与血小板抵抗的关系[J].广东医学,2014,(16):2526-2529,4.

基金项目

广东省科技计划项目 ()

广东医学

OA北大核心CSTPCD

1001-9448

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